SEC_13F_analysis_biotech

Report for Combined Biotech 13F Filings for quarter ending on 2025-09-30 (Compiled by Finradar.ai)
(Adar1, Avoro, Baker Brothers, BVF, Casdin, Cormorant, Deep Track, EcoR1, Logos, Opaleye, Orbimed, Perceptive, RA Capital, Tang)

Top 40 Stock Holdings by Value

	SYMBOL	DATE	Company	Float	First Traded	VALUE	SHARES	FUND_COUNT	FUND_LIST
0	ASND	2025-09-30	Ascendis Pharma A/S	59,372,631.00	2015-01-28	3321766586	16708247	5	adar1-avoro-perceptive-racapital-orbimed
1	INCY	2025-09-30	Incyte Corporation	161,370,279.00	1993-11-04	2615851059	30843663	2	baker-casdin
2	MDGL	2025-09-30	Madrigal Pharmaceuticals, Inc.	11,356,312.00	2007-02-06	1859681002	4054596	4	adar1-avoro-baker-ecor1
3	RYTM	2025-09-30	Rhythm Pharmaceuticals, Inc.	46,955,630.00	2017-10-09	1521707219	431317234	7	adar1-baker-logos-perceptive-racapital-orbimed-opaleye
4	INSM	2025-09-30	Insmed Incorporated	166,410,802.00	2000-06-01	1159147003	8049073	5	baker-cormorant-perceptive-orbimed-tang
5	KYMR	2025-09-30	Kymera Therapeutics, Inc.	42,816,370.00	2020-08-21	1071094721	18923935	5	avoro-baker-bvf-logos-perceptive
6	RNA	2025-09-30	Avidity Biosciences, Inc.	92,698,110.00	2020-06-12	960656326	22048573	9	adar1-avoro-baker-casdin-cormorant-ecor1-logos-racapital-orbimed
7	ACAD	2025-09-30	ACADIA Pharmaceuticals Inc.	114,380,229.00	2004-05-27	949667879	44501775	3	baker-deeptrack-tang
8	UTHR	2025-09-30	United Therapeutics Corporation	41,324,592.00	1999-06-17	900598066	2148322	3	adar1-avoro-orbimed
9	ARGX	2025-09-30	argenx SE	60,989,637.00	2017-05-18	885116254	1200060	3	avoro-baker-orbimed
10	RVMD	2025-09-30	Revolution Medicines, Inc.	168,212,518.00	2020-02-13	848386711	18166739	7	adar1-baker-bvf-casdin-logos-opaleye-tang
11	SMMT	2025-09-30	Summit Therapeutics Inc.	111,183,085.00	2015-03-05	710206983	34375943	3	adar1-baker-tang
12	EWTX	2025-09-30	Edgewise Therapeutics, Inc.	54,187,991.00	2021-03-26	681727622	42030063	8	adar1-baker-cormorant-perceptive-racapital-orbimed-opaleye-tang
13	CELC	2025-09-30	Celcuity Inc.	20,768,907.00	2017-09-20	630568869	12764552	5	baker-bvf-perceptive-orbimed-tang
14	PCVX	2025-09-30	Vaxcyte, Inc.	119,134,116.00	2020-06-12	609456239	16919940	7	adar1-baker-cormorant-deeptrack-logos-racapital-tang
15	APLS	2025-09-30	Apellis Pharmaceuticals, Inc.	84,226,131.00	2017-11-09	588677087	26013128	5	adar1-avoro-deeptrack-ecor1-orbimed
16	QURE	2025-09-30	uniQure N.V.	44,295,995.00	2014-02-05	585353213	10028323	8	adar1-avoro-deeptrack-ecor1-logos-perceptive-racapital-orbimed
17	MRUS	2025-09-30	Merus N.V.	55,639,246.00	2016-05-19	574624095	6103283	5	adar1-avoro-baker-perceptive-tang
18	CDTX	2025-09-30	Cidara Therapeutics, Inc.	3,569,414.00	2015-04-15	546165436	5703482	6	adar1-baker-bvf-deeptrack-logos-racapital
19	ACLX	2025-09-30	Arcellx, Inc.	32,601,579.00	2022-02-04	545405817	6643189	6	adar1-baker-cormorant-logos-perceptive-racapital
20	GPCR	2025-09-30	Structure Therapeutics Inc.	148,959,516.00	2023-02-03	537832680	19208310	9	adar1-avoro-baker-bvf-casdin-deeptrack-logos-racapital-orbimed
21	AKRO	2025-09-30	Akero Therapeutics, Inc.	66,438,220.00	2019-06-20	529367434	11149272	7	adar1-avoro-baker-deeptrack-logos-perceptive-orbimed
22	KRYS	2025-09-30	Krystal Biotech, Inc.	22,823,920.00	2017-09-20	517946964	2934045	4	adar1-avoro-perceptive-orbimed
23	ZYME	2025-09-30	Zymeworks Inc.	38,672,223.00	2017-04-28	515810739	30199692	5	bvf-ecor1-perceptive-opaleye-tang
24	ABVX	2025-09-30	Abivax SA	30,875,904.00	2023-10-20	502460358	5918261	7	adar1-baker-bvf-cormorant-logos-perceptive-orbimed
25	PTGX	2025-09-30	Protagonist Therapeutics, Inc.	46,016,118.00	2016-08-11	445142315	6700923	6	adar1-bvf-deeptrack-logos-perceptive-opaleye
26	ARWR	2025-09-30	Arrowhead Pharmaceuticals, Inc.	108,000,510.00	1993-12-16	435283183	12620562	3	adar1-avoro-baker
27	CNTA	2025-09-30	Centessa Pharmaceuticals plc	93,006,626.00	2021-05-28	416194215	17162648	7	adar1-avoro-cormorant-ecor1-logos-perceptive-tang
28	JANX	2025-09-30	Janux Therapeutics, Inc.	37,290,619.00	2021-06-11	393105449	16084511	7	adar1-cormorant-logos-perceptive-racapital-orbimed-tang
29	TARS	2025-09-30	Tarsus Pharmaceuticals, Inc.	29,909,637.00	2020-10-16	353768783	5952697	4	cormorant-deeptrack-orbimed-tang
30	NAMS	2025-09-30	NewAmsterdam Pharma Company N.V	53,941,411.00	2021-02-09	353460767	12428297	3	adar1-cormorant-racapital
31	MLYS	2025-09-30	Mineralys Therapeutics, Inc.	33,142,194.00	2023-02-10	343990597	9071482	4	adar1-racapital-orbimed-tang
32	WGS	2025-09-30	GeneDx Holdings Corp.	18,444,224.00	2020-11-04	341019510	3165208	3	casdin-racapital-tang
33	ALKS	2025-09-30	Alkermes plc	160,028,503.00	1991-07-16	340126530	11337551	5	adar1-avoro-baker-ecor1-opaleye
34	IONS	2025-09-30	Ionis Pharmaceuticals, Inc.	157,589,727.00	1991-05-17	330944079	5058760	4	adar1-baker-deeptrack-tang
35	IMCR	2025-09-30	Immunocore Holdings plc	37,260,699.00	2021-02-05	321613214	8852552	5	baker-bvf-deeptrack-logos-tang
36	OCUL	2025-09-30	Ocular Therapeutix, Inc.	124,121,633.00	2014-07-25	315947232	27027137	4	avoro-deeptrack-logos-opaleye
37	XENE	2025-09-30	Xenon Pharmaceuticals Inc.	70,775,310.00	2014-11-05	312354835	7779697	6	adar1-avoro-baker-deeptrack-perceptive-orbimed
38	IMVT	2025-09-30	Immunovant, Inc.	62,221,667.00	2019-06-21	310976868	19291369	5	adar1-baker-deeptrack-logos-perceptive
39	KOD	2025-09-30	Kodiak Sciences Inc	32,340,149.00	2018-10-04	295397746	18045067	3	baker-perceptive-tang

New Positions (Not previously in any of the funds) Sorted by Value

	SYMBOL	DATE	Company	Float	First Traded	VALUE	SHARES	FUND_COUNT	FUND_LIST	Position
0	VOR	2025-09-30	Vor Biopharma Inc.	38,992,387.00	2021-02-05	99013705	2032301	2	racapital-tang	New
1	BLTE	2025-09-30	Belite Bio, Inc	14,281,527.00	2022-04-29	68434312	924788	2	perceptive-racapital	New
2	DHR	2025-09-30	Danaher Corporation	634,598,025.00	1978-12-29	52162206	263100	1	orbimed	New
3	CI	2025-09-30	The Cigna Group	272,359,334.00	1982-03-31	46927100	162800	1	orbimed	New
4	PGEN	2025-09-30	Precigen, Inc.	147,094,997.00	2013-08-08	40796000	12400000	1	tang	New
5	TEM	2025-09-30	Tempus AI, Inc.	98,524,608.00	2024-06-14	30599340	379127	2	casdin-perceptive	New
6	ASMB	2025-09-30	Assembly Biosciences, Inc.	4,501,431.00	2010-12-17	26607539	1039357	2	adar1-racapital	New
7	IRTC	2025-09-30	iRhythm Technologies, Inc.	31,001,606.00	2016-10-20	21154770	123000	1	perceptive	New
8	IMA	2025-09-30	75244	NaN	2021-03-26 09:30:00	16782267	2059174	3	bvf-deeptrack-orbimed	New
9	CARL	2025-09-30	Carlsmed, Inc.	NaN	2025-07-23 09:30:00	16772314	1252600	1	orbimed	New
10	XFOR	2025-09-30	X4 Pharmaceuticals, Inc.	131,920,887.00	2017-11-16	11478293	3356226	2	bvf-deeptrack	New
11	INSP	2025-09-30	Inspire Medical Systems, Inc.	29,200,037.00	2018-05-03	8970854	120901	2	adar1-racapital	New
12	EQ	2025-09-30	Equillium, Inc.	18,182,775.00	2018-10-12	7950783	5559988	1	adar1	New
13	BTSG	2025-09-30	BrightSpring Health Services, I	69,664,071.00	2024-01-26	7797928	263800	1	orbimed	New
14	COGT	2025-09-30	Cogent Biosciences, Inc.	69,993,334.00	2018-03-29	7180000	500000	1	logos	New
15	ATAI	2025-09-30	ATAI Life Sciences N.V.	154,550,136.00	2021-06-18	6666680	1260242	2	adar1-orbimed	New
16	IMRX	2025-09-30	Immuneering Corporation	27,234,477.00	2021-07-30	6650000	950000	1	logos	New
17	MIST	2025-09-30	Milestone Pharmaceuticals Inc.	53,004,370.00	2019-05-09	6443656	3221828	1	orbimed	New
18	SLGL	2025-09-30	Sol-Gel Technologies Ltd.	8,240,005.00	2018-02-01	5970940	204835	1	opaleye	New
19	PLX	2025-09-30	Protalix BioTherapeutics, Inc.	59,149,480.00	1998-05-15	5728834	2580556	1	opaleye	New
20	EPRX	2025-09-30	Eupraxia Pharmaceuticals Inc.	24,915,659.00	2024-04-05	5310000	900000	1	logos	New
21	HTFL	2025-09-30	Heartflow, Inc.	79,410,281.00	2025-08-08 09:30:00	5049000	150000	1	perceptive	New
22	EVH	2025-09-30	Evolent Health, Inc	113,203,505.00	2015-06-05	4898780	579052	1	racapital	New
23	TMCI	2025-09-30	Treace Medical Concepts, Inc.	47,365,889.00	2021-04-23	4712064	702245	1	opaleye	New
24	GKOS	2025-09-30	Glaukos Corporation	54,680,371.00	2015-06-25	4418379	54180	1	racapital	New
25	ATHA	2025-09-30	Athira Pharma, Inc.	27,560,062.00	2020-09-18	2485217	600294	2	perceptive-tang	New
26	MASI	2025-09-30	Masimo Corporation	45,031,596.00	2007-08-08	2213250	15000	1	adar1	New
27	PGNY	2025-09-30	Progyny, Inc.	71,965,816.00	2019-10-25	2079435	96628	1	racapital	New
28	ESPR	2025-09-30	Esperion Therapeutics, Inc.	195,662,656.00	2013-06-26	1987500	750000	1	logos	New
29	CGTX	2025-09-30	Cognition Therapeutics, Inc.	55,626,916.00	2021-10-08	1620000	1200000	1	tang	New
30	GBIO	2025-09-30	Generation Bio Co.	48,781,725.00	2020-06-12	1325818	216637	2	adar1-baker	New
31	PASG	2025-09-30	Passage Bio, Inc.	48,820,577.00	2020-02-28	1076389	134046	2	orbimed-tang	New
32	RIGL	2025-09-30	Rigel Pharmaceuticals, Inc.	15,340,708.00	2000-11-29	1070506	37787	1	opaleye	New
33	MREO	2025-09-30	Mereo BioPharma Group plc	486,079,784.00	2019-04-24	1030000	500000	1	logos	New
34	BDSX	2025-09-30	Biodesix, Inc.	66,204,129.00	2020-10-28	820639	108694	1	perceptive	New
35	GUTS	2025-09-30	Fractyl Health, Inc.	18,121,028.00	2024-02-02	815824	513097	2	adar1-logos	New
36	SUPN	2025-09-30	Supernus Pharmaceuticals, Inc.	48,489,960.00	2012-05-01	689036	14418	1	adar1	New
37	NVCR	2025-09-30	NovoCure Limited	94,501,988.00	2015-10-01	439280	34000	1	adar1	New
38	INBS	2025-09-30	Intelligent Bio Solutions Inc.	5,197,640.00	2020-12-23	434962	426433	1	adar1	New
39	KPTI	2025-09-30	Karyopharm Therapeutics Inc.	7,241,049.00	2013-11-06	163500	25000	1	adar1	New

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New Positions (Not previously in any of the funds) Sorted by Number of Funds initiating the new position

	SYMBOL	DATE	Company	Float	First Traded	VALUE	SHARES	FUND_COUNT	FUND_LIST
0	IMA	2025-09-30	75244	NaN	2021-03-26 09:30:00	16782267	2059174	3	bvf-deeptrack-orbimed
1	VOR	2025-09-30	Vor Biopharma Inc.	38,992,387.00	2021-02-05	99013705	2032301	2	racapital-tang
2	BLTE	2025-09-30	Belite Bio, Inc	14,281,527.00	2022-04-29	68434312	924788	2	perceptive-racapital
3	GBIO	2025-09-30	Generation Bio Co.	48,781,725.00	2020-06-12	1325818	216637	2	adar1-baker
4	ATAI	2025-09-30	ATAI Life Sciences N.V.	154,550,136.00	2021-06-18	6666680	1260242	2	adar1-orbimed
5	PASG	2025-09-30	Passage Bio, Inc.	48,820,577.00	2020-02-28	1076389	134046	2	orbimed-tang
6	XFOR	2025-09-30	X4 Pharmaceuticals, Inc.	131,920,887.00	2017-11-16	11478293	3356226	2	bvf-deeptrack
7	INSP	2025-09-30	Inspire Medical Systems, Inc.	29,200,037.00	2018-05-03	8970854	120901	2	adar1-racapital
8	GUTS	2025-09-30	Fractyl Health, Inc.	18,121,028.00	2024-02-02	815824	513097	2	adar1-logos
9	ASMB	2025-09-30	Assembly Biosciences, Inc.	4,501,431.00	2010-12-17	26607539	1039357	2	adar1-racapital
10	TEM	2025-09-30	Tempus AI, Inc.	98,524,608.00	2024-06-14	30599340	379127	2	casdin-perceptive
11	ATHA	2025-09-30	Athira Pharma, Inc.	27,560,062.00	2020-09-18	2485217	600294	2	perceptive-tang
12	BDSX	2025-09-30	Biodesix, Inc.	66,204,129.00	2020-10-28	820639	108694	1	perceptive
13	GKOS	2025-09-30	Glaukos Corporation	54,680,371.00	2015-06-25	4418379	54180	1	racapital
14	MREO	2025-09-30	Mereo BioPharma Group plc	486,079,784.00	2019-04-24	1030000	500000	1	logos
15	RIGL	2025-09-30	Rigel Pharmaceuticals, Inc.	15,340,708.00	2000-11-29	1070506	37787	1	opaleye
16	SUPN	2025-09-30	Supernus Pharmaceuticals, Inc.	48,489,960.00	2012-05-01	689036	14418	1	adar1
17	NVCR	2025-09-30	NovoCure Limited	94,501,988.00	2015-10-01	439280	34000	1	adar1
18	CGTX	2025-09-30	Cognition Therapeutics, Inc.	55,626,916.00	2021-10-08	1620000	1200000	1	tang
19	ESPR	2025-09-30	Esperion Therapeutics, Inc.	195,662,656.00	2013-06-26	1987500	750000	1	logos
20	PGNY	2025-09-30	Progyny, Inc.	71,965,816.00	2019-10-25	2079435	96628	1	racapital
21	INBS	2025-09-30	Intelligent Bio Solutions Inc.	5,197,640.00	2020-12-23	434962	426433	1	adar1
22	MASI	2025-09-30	Masimo Corporation	45,031,596.00	2007-08-08	2213250	15000	1	adar1
23	EPRX	2025-09-30	Eupraxia Pharmaceuticals Inc.	24,915,659.00	2024-04-05	5310000	900000	1	logos
24	TMCI	2025-09-30	Treace Medical Concepts, Inc.	47,365,889.00	2021-04-23	4712064	702245	1	opaleye
25	EVH	2025-09-30	Evolent Health, Inc	113,203,505.00	2015-06-05	4898780	579052	1	racapital
26	HTFL	2025-09-30	Heartflow, Inc.	79,410,281.00	2025-08-08 09:30:00	5049000	150000	1	perceptive
27	PLX	2025-09-30	Protalix BioTherapeutics, Inc.	59,149,480.00	1998-05-15	5728834	2580556	1	opaleye
28	SLGL	2025-09-30	Sol-Gel Technologies Ltd.	8,240,005.00	2018-02-01	5970940	204835	1	opaleye
29	MIST	2025-09-30	Milestone Pharmaceuticals Inc.	53,004,370.00	2019-05-09	6443656	3221828	1	orbimed
30	IMRX	2025-09-30	Immuneering Corporation	27,234,477.00	2021-07-30	6650000	950000	1	logos
31	COGT	2025-09-30	Cogent Biosciences, Inc.	69,993,334.00	2018-03-29	7180000	500000	1	logos
32	BTSG	2025-09-30	BrightSpring Health Services, I	69,664,071.00	2024-01-26	7797928	263800	1	orbimed
33	EQ	2025-09-30	Equillium, Inc.	18,182,775.00	2018-10-12	7950783	5559988	1	adar1
34	CARL	2025-09-30	Carlsmed, Inc.	NaN	2025-07-23 09:30:00	16772314	1252600	1	orbimed
35	IRTC	2025-09-30	iRhythm Technologies, Inc.	31,001,606.00	2016-10-20	21154770	123000	1	perceptive
36	PGEN	2025-09-30	Precigen, Inc.	147,094,997.00	2013-08-08	40796000	12400000	1	tang
37	CI	2025-09-30	The Cigna Group	272,359,334.00	1982-03-31	46927100	162800	1	orbimed
38	DHR	2025-09-30	Danaher Corporation	634,598,025.00	1978-12-29	52162206	263100	1	orbimed
39	KPTI	2025-09-30	Karyopharm Therapeutics Inc.	7,241,049.00	2013-11-06	163500	25000	1	adar1

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Increased Positions (when all funds shares were added together) Sorted by Value

	SYMBOL	DATE	Company	Float	First Traded	VALUE	SHARES	FUND_COUNT	FUND_LIST	PCT_CHANGE	Position
0	ASND	2025-09-30	Ascendis Pharma A/S	59,372,631.00	2015-01-28	3321766586	16708247	5	adar1-avoro-perceptive-racapital-orbimed	2.75%	Increased
1	INCY	2025-09-30	Incyte Corporation	161,370,279.00	1993-11-04	2615851059	30843663	2	baker-casdin	0.33%	Increased
2	MDGL	2025-09-30	Madrigal Pharmaceuticals, Inc.	11,356,312.00	2007-02-06	1859681002	4054596	4	adar1-avoro-baker-ecor1	1.95%	Increased
3	RYTM	2025-09-30	Rhythm Pharmaceuticals, Inc.	46,955,630.00	2017-10-09	1521707219	431317234	7	adar1-baker-logos-perceptive-racapital-orbimed-opaleye	2878.08%	Increased
4	RNA	2025-09-30	Avidity Biosciences, Inc.	92,698,110.00	2020-06-12	960656326	22048573	9	adar1-avoro-baker-casdin-cormorant-ecor1-logos-racapital-orbimed	12.76%	Increased
5	ACAD	2025-09-30	ACADIA Pharmaceuticals Inc.	114,380,229.00	2004-05-27	949667879	44501775	3	baker-deeptrack-tang	0.24%	Increased
6	SMMT	2025-09-30	Summit Therapeutics Inc.	111,183,085.00	2015-03-05	710206983	34375943	3	adar1-baker-tang	1.15%	Increased
7	CELC	2025-09-30	Celcuity Inc.	20,768,907.00	2017-09-20	630568869	12764552	5	baker-bvf-perceptive-orbimed-tang	20.99%	Increased
8	PCVX	2025-09-30	Vaxcyte, Inc.	119,134,116.00	2020-06-12	609456239	16919940	7	adar1-baker-cormorant-deeptrack-logos-racapital-tang	10.37%	Increased
9	QURE	2025-09-30	uniQure N.V.	44,295,995.00	2014-02-05	585353213	10028323	8	adar1-avoro-deeptrack-ecor1-logos-perceptive-racapital-orbimed	31.71%	Increased
10	CDTX	2025-09-30	Cidara Therapeutics, Inc.	3,569,414.00	2015-04-15	546165436	5703482	6	adar1-baker-bvf-deeptrack-logos-racapital	17.82%	Increased
11	ACLX	2025-09-30	Arcellx, Inc.	32,601,579.00	2022-02-04	545405817	6643189	6	adar1-baker-cormorant-logos-perceptive-racapital	2.28%	Increased
12	GPCR	2025-09-30	Structure Therapeutics Inc.	148,959,516.00	2023-02-03	537832680	19208310	9	adar1-avoro-baker-bvf-casdin-deeptrack-logos-racapital-orbimed	35.07%	Increased
13	AKRO	2025-09-30	Akero Therapeutics, Inc.	66,438,220.00	2019-06-20	529367434	11149272	7	adar1-avoro-baker-deeptrack-logos-perceptive-orbimed	15.33%	Increased
14	KRYS	2025-09-30	Krystal Biotech, Inc.	22,823,920.00	2017-09-20	517946964	2934045	4	adar1-avoro-perceptive-orbimed	5.95%	Increased
15	ZYME	2025-09-30	Zymeworks Inc.	38,672,223.00	2017-04-28	515810739	30199692	5	bvf-ecor1-perceptive-opaleye-tang	1.12%	Increased
16	ARWR	2025-09-30	Arrowhead Pharmaceuticals, Inc.	108,000,510.00	1993-12-16	435283183	12620562	3	adar1-avoro-baker	8.85%	Increased
17	CNTA	2025-09-30	Centessa Pharmaceuticals plc	93,006,626.00	2021-05-28	416194215	17162648	7	adar1-avoro-cormorant-ecor1-logos-perceptive-tang	89.01%	Increased
18	TARS	2025-09-30	Tarsus Pharmaceuticals, Inc.	29,909,637.00	2020-10-16	353768783	5952697	4	cormorant-deeptrack-orbimed-tang	26.58%	Increased
19	NAMS	2025-09-30	NewAmsterdam Pharma Company N.V	53,941,411.00	2021-02-09	353460767	12428297	3	adar1-cormorant-racapital	0.02%	Increased
20	MLYS	2025-09-30	Mineralys Therapeutics, Inc.	33,142,194.00	2023-02-10	343990597	9071482	4	adar1-racapital-orbimed-tang	22.43%	Increased
21	ALKS	2025-09-30	Alkermes plc	160,028,503.00	1991-07-16	340126530	11337551	5	adar1-avoro-baker-ecor1-opaleye	15.04%	Increased
22	IMCR	2025-09-30	Immunocore Holdings plc	37,260,699.00	2021-02-05	321613214	8852552	5	baker-bvf-deeptrack-logos-tang	13.09%	Increased
23	OCUL	2025-09-30	Ocular Therapeutix, Inc.	124,121,633.00	2014-07-25	315947232	27027137	4	avoro-deeptrack-logos-opaleye	6.03%	Increased
24	IMVT	2025-09-30	Immunovant, Inc.	62,221,667.00	2019-06-21	310976868	19291369	5	adar1-baker-deeptrack-logos-perceptive	7.74%	Increased
25	KOD	2025-09-30	Kodiak Sciences Inc	32,340,149.00	2018-10-04	295397746	18045067	3	baker-perceptive-tang	3.64%	Increased
26	ANAB	2025-09-30	AnaptysBio, Inc.	18,032,374.00	2017-01-26	282124504	9213733	2	ecor1-tang	0.03%	Increased
27	CRNX	2025-09-30	Crinetics Pharmaceuticals, Inc.	91,642,575.00	2018-07-18	263040075	6315488	5	adar1-baker-cormorant-ecor1-orbimed	2.35%	Increased
28	NUVL	2025-09-30	Nuvalent, Inc.	40,974,058.00	2021-07-29	260700100	3014571	5	adar1-baker-perceptive-racapital-tang	90.68%	Increased
29	ROIV	2025-09-30	Roivant Sciences Ltd.	370,553,369.00	2020-12-08	260213804	17198533	4	adar1-baker-perceptive-orbimed	45.51%	Increased
30	VRDN	2025-09-30	Viridian Therapeutics, Inc.	76,929,941.00	2014-06-18	248858056	11531884	5	adar1-baker-deeptrack-perceptive-tang	8.94%	Increased
31	LENZ	2025-09-30	LENZ Therapeutics, Inc.	11,210,776.00	2021-06-25	237001741	5088058	3	adar1-racapital-tang	0.23%	Increased
32	SPRY	2025-09-30	ARS Pharmaceuticals, Inc.	47,452,700.00	2020-12-04	209127607	20808717	4	adar1-casdin-racapital-orbimed	2.76%	Increased
33	KNSA	2025-09-30	Kiniksa Pharmaceuticals, Ltd.	23,218,552.00	2018-05-25	203021295	5228465	3	adar1-baker-tang	0.36%	Increased
34	GLPG	2025-09-30	Galapagos NV	44,538,512.00	2012-02-27	201546362	5818313	2	ecor1-tang	15.74%	Increased
35	MBX	2025-09-30	MBX Biosciences, Inc.	13,610,404.00	2024-09-13	193064691	11032268	6	baker-cormorant-deeptrack-ecor1-orbimed-opaleye	27.42%	Increased
36	IMTX	2025-09-30	Immatics N.V.	61,326,922.00	2018-12-12	186964167	21944151	3	baker-perceptive-orbimed	8.25%	Increased
37	SLNO	2025-09-30	Soleno Therapeutics, Inc.	31,320,071.00	2014-11-13	179343273	2653007	3	adar1-avoro-tang	4.13%	Increased
38	PRAX	2025-09-30	Praxis Precision Medicines, Inc	16,083,216.00	2020-10-16	179089226	3379042	4	baker-cormorant-logos-perceptive	2.63%	Increased
39	STOK	2025-09-30	Stoke Therapeutics, Inc.	37,143,295.00	2019-06-19	175614349	7472951	4	baker-bvf-opaleye-tang	25.02%	Increased
40	AMLX	2025-09-30	Amylyx Pharmaceuticals, Inc.	58,959,626.00	2022-01-07	171494479	12619167	6	adar1-cormorant-logos-perceptive-orbimed-tang	32.55%	Increased
41	IDYA	2025-09-30	IDEAYA Biosciences, Inc.	86,629,628.00	2019-05-23	161775531	5945444	4	adar1-baker-logos-tang	8.82%	Increased
42	RAPP	2025-09-30	Rapport Therapeutics, Inc.	14,741,641.00	2024-06-07	152762960	5143534	3	baker-cormorant-perceptive	35.42%	Increased
43	ISRG	2025-09-30	Intuitive Surgical, Inc.	354,513,456.00	2000-06-16	151753636	339319	2	perceptive-orbimed	0.95%	Increased
44	BBIO	2025-09-30	BridgeBio Pharma, Inc.	139,058,316.00	2019-06-27	149245123	2873414	3	adar1-cormorant-deeptrack	4.12%	Increased
45	EYPT	2025-09-30	EyePoint Pharmaceuticals, Inc.	43,542,419.00	2005-01-27	144123040	10121000	2	cormorant-orbimed	21.57%	Increased
46	EXAS	2025-09-30	Exact Sciences Corporation	184,254,502.00	2001-02-01	142521848	2605042	5	casdin-deeptrack-perceptive-racapital-orbimed	273.58%	Increased
47	WVE	2025-09-30	Wave Life Sciences Ltd.	70,126,228.00	2015-11-11	136628817	18665139	3	adar1-baker-racapital	0.02%	Increased
48	CMPX	2025-09-30	Compass Therapeutics, Inc.	83,586,239.00	2021-04-05	136086850	38881957	5	adar1-bvf-logos-orbimed-tang	35.28%	Increased
49	TVTX	2025-09-30	Travere Therapeutics, Inc.	75,506,943.00	2012-11-08	134906299	5644615	3	perceptive-racapital-tang	110.29%	Increased
50	TNGX	2025-09-30	Tango Therapeutics, Inc.	46,645,311.00	2020-09-03	130874503	15580298	5	avoro-deeptrack-ecor1-logos-racapital	23.35%	Increased
51	CTMX	2025-09-30	CytomX Therapeutics, Inc.	73,975,451.00	2015-10-08	128126089	40164918	6	adar1-baker-perceptive-racapital-orbimed-tang	12.36%	Increased
52	AUPH	2025-09-30	Aurinia Pharmaceuticals Inc	133,424,854.00	2014-09-03	125190975	11329500	1	tang	12.85%	Increased
53	ORIC	2025-09-30	Oric Pharmaceuticals, Inc.	46,231,360.00	2020-04-24	124438464	10369872	2	ecor1-orbimed	311.94%	Increased
54	PEPG	2025-09-30	PepGen Inc.	10,471,699.00	2022-05-06	118601207	25671257	8	adar1-bvf-deeptrack-ecor1-logos-perceptive-racapital-opaleye	134.44%	Increased
55	OLMA	2025-09-30	Olema Pharmaceuticals, Inc.	41,105,755.00	2020-11-19	117589060	12011140	4	adar1-bvf-deeptrack-logos	0.53%	Increased
56	NRIX	2025-09-30	Nurix Therapeutics, Inc.	59,122,228.00	2020-07-24	105211242	11386498	4	adar1-baker-deeptrack-perceptive	2.81%	Increased
57	LAB	2025-09-30	Standard BioTools Inc.	48,240,936.00	2011-02-10	101356595	77966611	2	casdin-tang	1.94%	Increased
58	FULC	2025-09-30	Fulcrum Therapeutics, Inc.	26,503,299.00	2019-07-18	97250541	10570711	2	adar1-racapital	2.80%	Increased
59	CRSP	2025-09-30	CRISPR Therapeutics AG	85,368,761.00	2016-10-19	96519978	1489276	2	ecor1-tang	7.20%	Increased
60	PTCT	2025-09-30	PTC Therapeutics, Inc.	63,207,489.00	2013-06-20	92055000	1500000	1	tang	36.36%	Increased
61	DRUG	2025-09-30	Bright Minds Biosciences Inc.	2,524,284.00	2021-03-22	91512949	1508621	2	cormorant-perceptive	1.93%	Increased
62	LQDA	2025-09-30	Liquidia Corporation	66,205,312.00	2018-07-26	85474180	3758759	2	opaleye-tang	3.87%	Increased
63	FDMT	2025-09-30	4D Molecular Therapeutics, Inc.	34,309,158.00	2020-12-11	80028052	9209212	3	adar1-bvf-racapital	0.18%	Increased
64	NKTR	2025-09-30	Nektar Therapeutics	173,991,966.00	1994-05-03	76735454	1348602	2	adar1-bvf	8437.62%	Increased
65	APGE	2025-09-30	Apogee Therapeutics, Inc.	39,041,674.00	2023-07-14	76092724	1915246	3	perceptive-opaleye-tang	36.78%	Increased
66	ARVN	2025-09-30	Arvinas, Inc.	53,685,383.00	2018-09-27	68494060	8039209	4	adar1-logos-opaleye-tang	23.63%	Increased
67	DNLI	2025-09-30	Denali Therapeutics Inc.	131,342,965.00	2017-12-08	67855023	4673211	3	adar1-baker-casdin	0.34%	Increased
68	REPL	2025-09-30	Replimune Group, Inc.	53,003,113.00	2018-07-20	64627524	15424230	3	adar1-baker-tang	2.11%	Increased
69	BNTX	2025-09-30	BioNTech SE	92,355,164.00	2019-10-10	63996786	648923	3	adar1-baker-tang	1.57%	Increased
70	NGNE	2025-09-30	Neurogene Inc.	5,545,438.00	2014-03-07	62197838	3589027	4	adar1-baker-casdin-ecor1	0.03%	Increased
71	KALV	2025-09-30	KalVista Pharmaceuticals, Inc.	29,072,212.00	2015-04-09	61530900	5051798	2	adar1-tang	2.02%	Increased
72	CMPS	2025-09-30	COMPASS Pathways Plc – American	71,549,218.00	2020-09-18	59161018	10324785	3	deeptrack-ecor1-tang	1.91%	Increased
73	PEN	2025-09-30	Penumbra, Inc.	37,159,032.00	2015-09-18	55868966	220547	1	perceptive	572.46%	Increased
74	TRVI	2025-09-30	Trevi Therapeutics, Inc.	73,666,058.00	2019-05-07	53970360	5898400	3	logos-orbimed-opaleye	28.83%	Increased
75	MNPR	2025-09-30	Monopar Therapeutics Inc.	3,503,249.00	2019-12-19	52367294	641206	2	adar1-racapital	4.74%	Increased
76	SRRK	2025-09-30	Scholar Rock Holding Corporatio	69,786,242.00	2018-05-25	50716225	1361875	3	adar1-logos-racapital	15.79%	Increased
77	VSTM	2025-09-30	Verastem, Inc.	38,014,694.00	2012-01-27	50572686	5727371	3	logos-orbimed-tang	22.53%	Increased
78	PHVS	2025-09-30	Pharvaris N.V.	19,413,727.00	2021-02-05	47961984	1922324	4	adar1-baker-cormorant-logos	29.12%	Increased
79	NTLA	2025-09-30	Intellia Therapeutics, Inc.	97,913,025.00	2016-05-06	47435060	2746674	1	baker	2.65%	Increased
80	CRBP	2025-09-30	Corbus Pharmaceuticals Holdings	7,526,368.00	2014-10-27	46615339	3685007	4	adar1-cormorant-orbimed-tang	0.28%	Increased
81	BEAM	2025-09-30	Beam Therapeutics Inc.	73,199,019.00	2020-02-06	45020850	1855000	2	casdin-tang	12.08%	Increased
82	INBX	2025-09-30	Inhibrx Biosciences, Inc.	7,712,906.00	2024-06-04	44717171	1327707	1	perceptive	35.77%	Increased
83	PRME	2025-09-30	Prime Medicine, Inc.	60,638,823.00	2022-10-20	42716176	7710501	3	casdin-ecor1-racapital	392.00%	Increased
84	CBIO	2025-09-30	Crescent Biopharma, Inc.	NaN	2014-01-10 09:30:00	42507451	3575059	5	bvf-deeptrack-logos-perceptive-tang	23.32%	Increased
85	VKTX	2025-09-30	Viking Therapeutics, Inc.	109,861,197.00	2015-04-28	39882501	1517599	4	adar1-baker-perceptive-tang	85.41%	Increased
86	CTNM	2025-09-30	Contineum Therapeutics, Inc.	13,299,011.00	2024-04-05	36901534	3140556	5	adar1-baker-casdin-perceptive-racapital	136.64%	Increased
87	ERAS	2025-09-30	Erasca, Inc.	201,634,202.00	2021-07-16	36303355	16652915	2	logos-tang	0.91%	Increased
88	RGEN	2025-09-30	Repligen Corporation	52,524,167.00	1986-04-29	36148111	270428	1	perceptive	62.91%	Increased
89	AQST	2025-09-30	Aquestive Therapeutics, Inc.	94,253,087.00	2018-07-25	35692703	6385099	2	ecor1-perceptive	191.50%	Increased
90	URGN	2025-09-30	UroGen Pharma Ltd.	36,992,561.00	2017-05-04	34393800	1724000	3	adar1-orbimed-tang	15.83%	Increased
91	ANNX	2025-09-30	Annexon, Inc.	81,750,277.00	2020-07-24	29280000	9600000	2	bvf-opaleye	2.02%	Increased
92	IVVD	2025-09-30	Invivyd, Inc.	47,996,574.00	2021-08-06	27379092	24890083	3	adar1-racapital-tang	176.99%	Increased
93	ALDX	2025-09-30	Aldeyra Therapeutics, Inc.	47,818,870.00	2014-05-02	27260463	5222311	1	perceptive	21.41%	Increased
94	ADCT	2025-09-30	ADC Therapeutics SA	73,042,624.00	2020-05-18	26359520	6589880	2	orbimed-opaleye	11.55%	Increased
95	GMAB	2025-09-30	Genmab A/S	62,846,320.00	2009-06-01	20894459	681267	2	deeptrack-tang	240.63%	Increased
96	DERM	2025-09-30	Journey Medical Corporation	10,945,727.00	2021-11-12	20118700	2825660	2	opaleye-tang	44.94%	Increased
97	GOSS	2025-09-30	Gossamer Bio, Inc.	183,672,034.00	2019-02-08	19857363	7550328	4	adar1-perceptive-opaleye-tang	100.16%	Increased
98	IKT	2025-09-30	Inhibikase Therapeutics, Inc.	25,709,535.00	2020-12-23	17284057	10669171	2	adar1-perceptive	1.09%	Increased
99	NUVB	2025-09-30	Nuvation Bio Inc.	228,079,888.00	2020-08-26	15540000	4200000	1	tang	7.69%	Increased
100	PMVP	2025-09-30	PMV Pharmaceuticals, Inc.	34,407,051.00	2020-09-25	15206099	10861500	3	adar1-orbimed-tang	65.16%	Increased
101	STTK	2025-09-30	Shattuck Labs, Inc.	24,176,183.00	2020-10-09	15071644	6306127	1	orbimed	6025.55%	Increased
102	REGN	2025-09-30	Regeneron Pharmaceuticals, Inc.	102,996,273.00	1991-04-02	14450339	25700	2	adar1-tang	92.35%	Increased
103	CABA	2025-09-30	Cabaletta Bio, Inc.	42,831,744.00	2019-10-25	13592784	5808882	2	cormorant-opaleye	16.18%	Increased
104	ABUS	2025-09-30	Arbutus Biopharma Corporation	136,309,001.00	2007-07-26	13180646	2903226	1	adar1	2.74%	Increased
105	OBIO	2025-09-30	Orchestra BioMed Holdings, Inc.	18,386,175.00	2020-08-04	13125539	5292556	1	perceptive	15.24%	Increased
106	VTYX	2025-09-30	Ventyx Biosciences, Inc.	54,957,214.00	2021-10-21	13076710	4204730	3	adar1-baker-tang	28.64%	Increased
107	VTGN	2025-09-30	VistaGen Therapeutics, Inc.	20,224,817.00	2011-06-21	11264370	3173062	2	adar1-orbimed	654.12%	Increased
108	LXEO	2025-09-30	Lexeo Therapeutics, Inc.	21,795,488.00	2023-11-03	11100672	1671788	2	adar1-perceptive	486.71%	Increased
109	SABS	2025-09-30	SAB Biotherapeutics, Inc.	6,791,463.00	2021-02-09	10751886	5349197	3	adar1-bvf-racapital	482.81%	Increased
110	HRTX	2025-09-30	Heron Therapeutics, Inc.	115,963,945.00	1987-08-26	9704458	7701951	2	baker-tang	260.67%	Increased
111	BHC	2025-09-30	Bausch Health Companies Inc.	276,207,976.00	1994-03-29	8385000	1300000	1	tang	76.43%	Increased
112	PYXS	2025-09-30	Pyxis Oncology, Inc.	44,339,556.00	2021-10-08	8165842	3678307	2	perceptive-tang	47.13%	Increased
113	HRMY	2025-09-30	Harmony Biosciences Holdings, I	44,329,878.00	2020-08-19	8032224	291445	2	adar1-tang	3.64%	Increased
114	CRMD	2025-09-30	CorMedix Inc.	60,890,203.00	2010-05-13	5815000	500000	1	deeptrack	185.71%	Increased
115	ESTA	2025-09-30	Establishment Labs Holdings Inc	16,562,689.00	2018-07-19	3717301	90688	1	adar1	262.75%	Increased
116	ACRS	2025-09-30	Aclaris Therapeutics, Inc.	66,068,981.00	2015-10-06	3559996	1873682	2	adar1-logos	1.28%	Increased
117	VTVT	2025-09-30	vTv Therapeutics Inc.	1,072,776.00	2015-07-30	3463132	148314	1	baker	52.41%	Increased
118	FENC	2025-09-30	Fennec Pharmaceuticals Inc.	14,403,520.00	2017-09-15	3131790	334593	1	tang	1530.01%	Increased
119	IFRX	2025-09-30	InflaRx N.V.	50,522,550.00	2017-11-07	2857834	2132712	2	adar1-racapital	8.08%	Increased
120	PFE	2025-09-30	Pfizer, Inc.	5,657,705,935.00	1972-06-01	2482758	97439	2	adar1-tang	5.41%	Increased
121	STRO	2025-09-30	Sutro Biopharma, Inc.	70,805,238.00	2018-09-27	2456458	2828717	1	tang	10.43%	Increased
122	DCTH	2025-09-30	Delcath Systems, Inc.	31,032,851.00	2018-05-03	2412139	224385	1	adar1	50.21%	Increased
123	OABI	2025-09-30	OmniAb, Inc.	99,520,435.00	2021-09-30	2225005	1390628	2	adar1-tang	122.11%	Increased
124	UNCY	2025-09-30	Unicycive Therapeutics, Inc.	70,600,827.00	2021-07-12	2064735	473563	1	logos	0.00%	Increased
125	ANRO	2025-09-30	Alto Neuroscience, Inc.	19,503,574.00	2024-02-02	1629571	405366	2	perceptive-orbimed	62.15%	Increased
126	BMRN	2025-09-30	BioMarin Pharmaceutical Inc.	178,517,719.00	1999-07-26	1611585	29756	2	adar1-deeptrack	507.27%	Increased
127	NVNO	2025-09-30	enVVeno Medical Corporation	17,374,493.00	2018-05-31	1593686	1759035	1	perceptive	36.89%	Increased
128	MRK	2025-09-30	Merck & Company, Inc.	2,522,019,842.00	1962-01-02	1556062	18540	1	adar1	163.35%	Increased
129	QNCX	2025-09-30	Quince Therapeutics, Inc.	32,660,220.00	2019-05-09	1263305	775034	1	adar1	442.14%	Increased
130	PACB	2025-09-30	Pacific Biosciences of Californ	295,618,336.00	2010-10-27	958422	748767	2	casdin-tang	3.45%	Increased
131	ATYR	2025-09-30	aTyr Pharma, Inc.	81,953,409.00	2015-05-07	610401	846134	2	adar1-tang	26.08%	Increased
132	KPRX	2025-09-30	Kiora Pharmaceuticals, Inc.	1,762,573.00	2015-02-13	466876	167941	1	adar1	0.50%	Increased
133	LUNG	2025-09-30	Pulmonx Corporation	38,129,348.00	2020-10-01	347485	214497	1	adar1	4.89%	Increased
134	ACHV	2025-09-30	Achieve Life Sciences, Inc.	29,417,797.00	1995-10-12	150570	47800	1	adar1	10.72%	Increased

------------------------------------------------------------
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Increased Positions (when all funds shares were added together) Sorted by Increase in Share %

	SYMBOL	DATE	Company	Float	First Traded	VALUE	SHARES	FUND_COUNT	FUND_LIST	PCT_CHANGE
0	NKTR	2025-09-30	Nektar Therapeutics	173,991,966.00	1994-05-03	76735454	1348602	2	adar1-bvf	8437.62%
1	STTK	2025-09-30	Shattuck Labs, Inc.	24,176,183.00	2020-10-09	15071644	6306127	1	orbimed	6025.55%
2	RYTM	2025-09-30	Rhythm Pharmaceuticals, Inc.	46,955,630.00	2017-10-09	1521707219	431317234	7	adar1-baker-logos-perceptive-racapital-orbimed-opaleye	2878.08%
3	FENC	2025-09-30	Fennec Pharmaceuticals Inc.	14,403,520.00	2017-09-15	3131790	334593	1	tang	1530.01%
4	VTGN	2025-09-30	VistaGen Therapeutics, Inc.	20,224,817.00	2011-06-21	11264370	3173062	2	adar1-orbimed	654.12%
5	PEN	2025-09-30	Penumbra, Inc.	37,159,032.00	2015-09-18	55868966	220547	1	perceptive	572.46%
6	BMRN	2025-09-30	BioMarin Pharmaceutical Inc.	178,517,719.00	1999-07-26	1611585	29756	2	adar1-deeptrack	507.27%
7	LXEO	2025-09-30	Lexeo Therapeutics, Inc.	21,795,488.00	2023-11-03	11100672	1671788	2	adar1-perceptive	486.71%
8	SABS	2025-09-30	SAB Biotherapeutics, Inc.	6,791,463.00	2021-02-09	10751886	5349197	3	adar1-bvf-racapital	482.81%
9	QNCX	2025-09-30	Quince Therapeutics, Inc.	32,660,220.00	2019-05-09	1263305	775034	1	adar1	442.14%
10	PRME	2025-09-30	Prime Medicine, Inc.	60,638,823.00	2022-10-20	42716176	7710501	3	casdin-ecor1-racapital	392.00%
11	ORIC	2025-09-30	Oric Pharmaceuticals, Inc.	46,231,360.00	2020-04-24	124438464	10369872	2	ecor1-orbimed	311.94%
12	EXAS	2025-09-30	Exact Sciences Corporation	184,254,502.00	2001-02-01	142521848	2605042	5	casdin-deeptrack-perceptive-racapital-orbimed	273.58%
13	ESTA	2025-09-30	Establishment Labs Holdings Inc	16,562,689.00	2018-07-19	3717301	90688	1	adar1	262.75%
14	HRTX	2025-09-30	Heron Therapeutics, Inc.	115,963,945.00	1987-08-26	9704458	7701951	2	baker-tang	260.67%
15	GMAB	2025-09-30	Genmab A/S	62,846,320.00	2009-06-01	20894459	681267	2	deeptrack-tang	240.63%
16	AQST	2025-09-30	Aquestive Therapeutics, Inc.	94,253,087.00	2018-07-25	35692703	6385099	2	ecor1-perceptive	191.50%
17	CRMD	2025-09-30	CorMedix Inc.	60,890,203.00	2010-05-13	5815000	500000	1	deeptrack	185.71%
18	IVVD	2025-09-30	Invivyd, Inc.	47,996,574.00	2021-08-06	27379092	24890083	3	adar1-racapital-tang	176.99%
19	MRK	2025-09-30	Merck & Company, Inc.	2,522,019,842.00	1962-01-02	1556062	18540	1	adar1	163.35%

------------------------------------------------------------
------------------------------------------------------------

Increased Positions (when all funds shares were added together) Sorted by the Highest Fund Number

	SYMBOL	DATE	Company	Float	First Traded	VALUE	SHARES	FUND_COUNT	FUND_LIST	PCT_CHANGE
0	RNA	2025-09-30	Avidity Biosciences, Inc.	92,698,110.00	2020-06-12	960656326	22048573	9	adar1-avoro-baker-casdin-cormorant-ecor1-logos-racapital-orbimed	12.76%
1	GPCR	2025-09-30	Structure Therapeutics Inc.	148,959,516.00	2023-02-03	537832680	19208310	9	adar1-avoro-baker-bvf-casdin-deeptrack-logos-racapital-orbimed	35.07%
2	PEPG	2025-09-30	PepGen Inc.	10,471,699.00	2022-05-06	118601207	25671257	8	adar1-bvf-deeptrack-ecor1-logos-perceptive-racapital-opaleye	134.44%
3	QURE	2025-09-30	uniQure N.V.	44,295,995.00	2014-02-05	585353213	10028323	8	adar1-avoro-deeptrack-ecor1-logos-perceptive-racapital-orbimed	31.71%
4	CNTA	2025-09-30	Centessa Pharmaceuticals plc	93,006,626.00	2021-05-28	416194215	17162648	7	adar1-avoro-cormorant-ecor1-logos-perceptive-tang	89.01%
5	RYTM	2025-09-30	Rhythm Pharmaceuticals, Inc.	46,955,630.00	2017-10-09	1521707219	431317234	7	adar1-baker-logos-perceptive-racapital-orbimed-opaleye	2878.08%
6	AKRO	2025-09-30	Akero Therapeutics, Inc.	66,438,220.00	2019-06-20	529367434	11149272	7	adar1-avoro-baker-deeptrack-logos-perceptive-orbimed	15.33%
7	PCVX	2025-09-30	Vaxcyte, Inc.	119,134,116.00	2020-06-12	609456239	16919940	7	adar1-baker-cormorant-deeptrack-logos-racapital-tang	10.37%
8	MBX	2025-09-30	MBX Biosciences, Inc.	13,610,404.00	2024-09-13	193064691	11032268	6	baker-cormorant-deeptrack-ecor1-orbimed-opaleye	27.42%
9	ACLX	2025-09-30	Arcellx, Inc.	32,601,579.00	2022-02-04	545405817	6643189	6	adar1-baker-cormorant-logos-perceptive-racapital	2.28%
10	CTMX	2025-09-30	CytomX Therapeutics, Inc.	73,975,451.00	2015-10-08	128126089	40164918	6	adar1-baker-perceptive-racapital-orbimed-tang	12.36%
11	CDTX	2025-09-30	Cidara Therapeutics, Inc.	3,569,414.00	2015-04-15	546165436	5703482	6	adar1-baker-bvf-deeptrack-logos-racapital	17.82%
12	AMLX	2025-09-30	Amylyx Pharmaceuticals, Inc.	58,959,626.00	2022-01-07	171494479	12619167	6	adar1-cormorant-logos-perceptive-orbimed-tang	32.55%
13	IMCR	2025-09-30	Immunocore Holdings plc	37,260,699.00	2021-02-05	321613214	8852552	5	baker-bvf-deeptrack-logos-tang	13.09%
14	VRDN	2025-09-30	Viridian Therapeutics, Inc.	76,929,941.00	2014-06-18	248858056	11531884	5	adar1-baker-deeptrack-perceptive-tang	8.94%
15	NUVL	2025-09-30	Nuvalent, Inc.	40,974,058.00	2021-07-29	260700100	3014571	5	adar1-baker-perceptive-racapital-tang	90.68%
16	CTNM	2025-09-30	Contineum Therapeutics, Inc.	13,299,011.00	2024-04-05	36901534	3140556	5	adar1-baker-casdin-perceptive-racapital	136.64%
17	CBIO	2025-09-30	Crescent Biopharma, Inc.	NaN	2014-01-10 09:30:00	42507451	3575059	5	bvf-deeptrack-logos-perceptive-tang	23.32%
18	CRNX	2025-09-30	Crinetics Pharmaceuticals, Inc.	91,642,575.00	2018-07-18	263040075	6315488	5	adar1-baker-cormorant-ecor1-orbimed	2.35%
19	IMVT	2025-09-30	Immunovant, Inc.	62,221,667.00	2019-06-21	310976868	19291369	5	adar1-baker-deeptrack-logos-perceptive	7.74%

------------------------------------------------------------
------------------------------------------------------------

Closed Positions (No longer in any in any of the funds) Sorted by Value

	SYMBOL	DATE	Company	Float	First Traded	VALUE	SHARES	FUND_COUNT	FUND_LIST	Position
0	THC	2025-06-30	Tenet Healthcare Corporation	93,879,671.00	1980-03-17	81840000	465000	1	orbimed	Closed
1	RXST	2025-06-30	RxSight, Inc.	32,215,490.00	2021-07-30	48138571	3702967	1	racapital	Closed
2	PODD	2025-06-30	Insulet Corporation	69,910,789.00	2007-05-15	18972388	60387	1	perceptive	Closed
3	HNGE	2025-06-30	Hinge Health, Inc.	4,695,728.00	2025-05-22 09:30:00	15525000	300000	1	racapital	Closed
4	CRL	2025-06-30	Charles River Laboratories Inte	50,549,899.00	2000-06-23	15173000	100000	1	perceptive	Closed
5	ELAN	2025-06-30	Elanco Animal Health Incorporat	490,780,682.00	2018-09-20	11425428	800100	1	tang	Closed
6	PCRX	2025-06-30	Pacira BioSciences, Inc.	43,487,172.00	2011-02-03	10933557	457471	1	ecor1	Closed
7	NVAX	2025-06-30	Novavax, Inc.	135,577,182.00	1995-12-05	10070815	1598542	2	deeptrack-tang	Closed
8	CPRX	2025-06-30	Catalyst Pharmaceuticals, Inc.	113,799,541.00	2006-11-08	9046730	416900	1	orbimed	Closed
9	ANIK	2025-06-30	Anika Therapeutics Inc.	10,199,202.00	1993-05-03	6229472	588797	1	opaleye	Closed
10	TXG	2025-06-30	10x Genomics, Inc.	106,469,868.00	2019-09-12	5504472	475343	1	racapital	Closed
11	GMED	2025-06-30	Globus Medical, Inc.	114,224,212.00	2012-08-03	5223270	88500	1	perceptive	Closed
12	INO	2025-06-30	Inovio Pharmaceuticals, Inc.	33,103,900.00	1998-12-08	4032088	1981370	1	deeptrack	Closed
13	ARDX	2025-06-30	Ardelyx, Inc.	231,291,344.00	2014-06-19	3587310	915130	1	adar1	Closed
14	ALEC	2025-06-30	Alector, Inc.	73,332,475.00	2019-02-07	2412936	1723526	1	adar1	Closed
15	RCEL	2025-06-30	Avita Medical, Inc.	25,848,578.00	2012-05-14	2060556	389519	1	opaleye	Closed
16	ACHC	2025-06-30	Acadia Healthcare Company, Inc.	90,430,406.00	1994-03-04	2025355	89262	1	racapital	Closed
17	CADL	2025-06-30	Candel Therapeutics, Inc.	35,925,874.00	2021-07-27	1796867	355112	1	baker	Closed
18	ALXO	2025-06-30	ALX Oncology Holdings Inc.	32,339,047.00	2020-07-17	1310996	3158265	1	tang	Closed
19	TPST	2025-06-30	Tempest Therapeutics, Inc.	3,222,289.00	2012-11-12	944942	138962	1	tang	Closed
20	APLT	2025-06-30	Applied Therapeutics, Inc.	103,058,488.00	2019-05-14	755403	2428169	1	tang	Closed
21	PYPD	2025-06-30	PolyPid Ltd.	4,590,187.00	2020-06-26	366944	103950	1	adar1	Closed
22	MCRB	2025-06-30	Seres Therapeutics, Inc.	128,451,837.00	2015-06-26	154662	13921	1	tang	Closed
23	AVXL	2025-06-30	Anavex Life Sciences Corp.	82,257,080.00	2006-08-02	149558	16221	1	adar1	Closed
24	RLMD	2025-06-30	Relmada Therapeutics, Inc.	30,568,156.00	2014-06-20	78039	130000	1	adar1	Closed
25	CASI	2025-06-30	CASI Pharmaceuticals, Inc.	7,353,446.00	1996-06-12	52062	44120	1	adar1	Closed
26	ACTU	2025-06-30	Actuate Therapeutics, Inc.	5,962,227.00	2024-08-13	32035	5243	1	tang	Closed
27	GALT	2025-06-30	Galectin Therapeutics Inc.	44,013,425.00	2002-09-04	27246	12913	1	tang	Closed
28	RNXT	2025-06-30	RenovoRx, Inc.	35,057,106.00	2021-08-26	26154	19889	1	adar1	Closed

------------------------------------------------------------
------------------------------------------------------------

Decreased Positions (when all funds shares were added together) Sorted by Value

	SYMBOL	DATE	Company	Float	First Traded	VALUE	SHARES	FUND_COUNT	FUND_LIST	PCT_CHANGE	Position
0	INSM	2025-09-30	Insmed Incorporated	166,410,802.00	2000-06-01	1159147003	8049073	5	baker-cormorant-perceptive-orbimed-tang	-25.93%	Decreased
1	KYMR	2025-09-30	Kymera Therapeutics, Inc.	42,816,370.00	2020-08-21	1071094721	18923935	5	avoro-baker-bvf-logos-perceptive	-0.05%	Decreased
2	UTHR	2025-09-30	United Therapeutics Corporation	41,324,592.00	1999-06-17	900598066	2148322	3	adar1-avoro-orbimed	-12.49%	Decreased
3	ARGX	2025-09-30	argenx SE	60,989,637.00	2017-05-18	885116254	1200060	3	avoro-baker-orbimed	-15.64%	Decreased
4	RVMD	2025-09-30	Revolution Medicines, Inc.	168,212,518.00	2020-02-13	848386711	18166739	7	adar1-baker-bvf-casdin-logos-opaleye-tang	-5.75%	Decreased
5	EWTX	2025-09-30	Edgewise Therapeutics, Inc.	54,187,991.00	2021-03-26	681727622	42030063	8	adar1-baker-cormorant-perceptive-racapital-orbimed-opaleye-tang	-1.29%	Decreased
6	APLS	2025-09-30	Apellis Pharmaceuticals, Inc.	84,226,131.00	2017-11-09	588677087	26013128	5	adar1-avoro-deeptrack-ecor1-orbimed	-20.25%	Decreased
7	MRUS	2025-09-30	Merus N.V.	55,639,246.00	2016-05-19	574624095	6103283	5	adar1-avoro-baker-perceptive-tang	-5.40%	Decreased
8	ABVX	2025-09-30	Abivax SA	30,875,904.00	2023-10-20	502460358	5918261	7	adar1-baker-bvf-cormorant-logos-perceptive-orbimed	-31.83%	Decreased
9	PTGX	2025-09-30	Protagonist Therapeutics, Inc.	46,016,118.00	2016-08-11	445142315	6700923	6	adar1-bvf-deeptrack-logos-perceptive-opaleye	-21.94%	Decreased
10	JANX	2025-09-30	Janux Therapeutics, Inc.	37,290,619.00	2021-06-11	393105449	16084511	7	adar1-cormorant-logos-perceptive-racapital-orbimed-tang	-4.96%	Decreased
11	WGS	2025-09-30	GeneDx Holdings Corp.	18,444,224.00	2020-11-04	341019510	3165208	3	casdin-racapital-tang	-13.64%	Decreased
12	IONS	2025-09-30	Ionis Pharmaceuticals, Inc.	157,589,727.00	1991-05-17	330944079	5058760	4	adar1-baker-deeptrack-tang	-28.78%	Decreased
13	XENE	2025-09-30	Xenon Pharmaceuticals Inc.	70,775,310.00	2014-11-05	312354835	7779697	6	adar1-avoro-baker-deeptrack-perceptive-orbimed	-8.78%	Decreased
14	GHRS	2025-09-30	GH Research PLC	17,280,108.00	2021-06-25	281636756	19694878	5	bvf-cormorant-deeptrack-racapital-tang	-3.99%	Decreased
15	JAZZ	2025-09-30	Jazz Pharmaceuticals plc	58,903,824.00	2007-06-01	276644114	2098969	4	adar1-ecor1-logos-tang	-10.65%	Decreased
16	SEPN	2025-09-30	Septerna, Inc.	19,629,806.00	2024-10-25	276580454	14703905	7	adar1-avoro-bvf-casdin-logos-perceptive-racapital	-0.67%	Decreased
17	CYTK	2025-09-30	Cytokinetics, Incorporated	117,836,397.00	2004-04-30	270343898	4918921	3	adar1-deeptrack-tang	-9.06%	Decreased
18	BSX	2025-09-30	Boston Scientific Corporation	1,471,454,074.00	1992-05-19	267437859	2739300	2	perceptive-orbimed	-11.44%	Decreased
19	GH	2025-09-30	Guardant Health, Inc.	111,589,027.00	2018-10-04	266170173	4260086	3	adar1-casdin-deeptrack	-2.07%	Decreased
20	AXSM	2025-09-30	Axsome Therapeutics, Inc.	36,674,021.00	2015-11-19	263237653	2167457	5	bvf-cormorant-deeptrack-perceptive-orbimed	-32.65%	Decreased
21	IRON	2025-09-30	Disc Medicine, Inc.	26,301,510.00	2020-08-12	262532470	3972949	5	baker-logos-racapital-orbimed-opaleye	-5.76%	Decreased
22	LLY	2025-09-30	Eli Lilly and Company	895,933,556.00	1972-06-01	238208600	312200	3	adar1-orbimed-tang	-12.45%	Decreased
23	TYRA	2025-09-30	Tyra Biosciences, Inc.	21,075,120.00	2021-09-15	221867774	15859026	3	baker-bvf-racapital	-6.48%	Decreased
24	VERA	2025-09-30	Vera Therapeutics, Inc.	50,541,557.00	2021-05-14	219693600	7560000	2	avoro-tang	-1.18%	Decreased
25	MIRM	2025-09-30	Mirum Pharmaceuticals, Inc.	38,862,861.00	2019-07-18	200232849	2731317	2	bvf-tang	-31.67%	Decreased
26	FOLD	2025-09-30	Amicus Therapeutics, Inc.	250,897,044.00	2007-05-31	181565058	23041251	3	avoro-perceptive-orbimed	-16.81%	Decreased
27	DVAX	2025-09-30	Dynavax Technologies Corporatio	99,188,424.00	2004-02-19	177209281	17845849	3	adar1-deeptrack-tang	-10.37%	Decreased
28	ELVN	2025-09-30	Enliven Therapeutics, Inc.	26,934,302.00	2020-03-12	176336175	8614371	4	baker-cormorant-logos-orbimed	-9.07%	Decreased
29	TSHA	2025-09-30	Taysha Gene Therapies, Inc.	127,701,667.00	2020-09-24	173297195	52996084	5	adar1-avoro-baker-racapital-tang	-0.33%	Decreased
30	MLTX	2025-09-30	MoonLake Immunotherapeutics	28,073,483.00	2020-10-20	171341145	23896952	4	adar1-avoro-bvf-cormorant	-26.76%	Decreased
31	BLFS	2025-09-30	BioLife Solutions, Inc.	36,395,390.00	1989-11-22	171099779	6707165	1	casdin	-12.97%	Decreased
32	ALNY	2025-09-30	Alnylam Pharmaceuticals, Inc.	124,460,110.00	2004-06-01	162609600	356600	2	casdin-orbimed	-15.78%	Decreased
33	DNTH	2025-09-30	Dianthus Therapeutics, Inc.	14,121,907.00	2018-06-21	162168592	4121184	4	baker-logos-racapital-tang	-33.04%	Decreased
34	ABCL	2025-09-30	AbCellera Biologics Inc.	202,801,468.00	2020-12-11	151531969	30125640	2	baker-tang	-9.99%	Decreased
35	BCAX	2025-09-30	Bicara Therapeutics Inc.	28,372,303.00	2024-09-13	148368445	9396355	3	adar1-deeptrack-racapital	-4.17%	Decreased
36	GERN	2025-09-30	Geron Corporation	601,237,820.00	1996-07-31	139646927	101932064	3	adar1-deeptrack-racapital	-1.82%	Decreased
37	KROS	2025-09-30	Keros Therapeutics, Inc.	30,728,590.00	2020-04-08	137269855	8676982	4	adar1-logos-orbimed-tang	-11.70%	Decreased
38	NBIX	2025-09-30	Neurocrine Biosciences, Inc.	98,515,061.00	1996-05-23	133879002	953690	3	perceptive-orbimed-tang	-4.02%	Decreased
39	EW	2025-09-30	Edwards Lifesciences Corporatio	581,838,751.00	2000-03-27	130964680	1684000	1	orbimed	-1.41%	Decreased
40	XNCR	2025-09-30	Xencor, Inc.	63,604,579.00	2013-12-03	125104179	10665318	5	adar1-baker-bvf-deeptrack-ecor1	-6.78%	Decreased
41	CGON	2025-09-30	CG Oncology, Inc.	60,853,824.00	2024-01-25	124798195	3098267	5	adar1-cormorant-orbimed-opaleye-tang	-8.32%	Decreased
42	TERN	2025-09-30	Terns Pharmaceuticals, Inc.	53,712,485.00	2021-02-05	113160462	15067971	3	adar1-deeptrack-orbimed	-0.12%	Decreased
43	SLDB	2025-09-30	Solid Biosciences Inc.	39,269,557.00	2018-01-26	108869416	17644962	2	perceptive-racapital	-0.41%	Decreased
44	RLAY	2025-09-30	Relay Therapeutics, Inc.	119,707,854.00	2020-07-16	107373083	20569556	3	baker-casdin-tang	-0.28%	Decreased
45	UPB	2025-09-30	Upstream Bio, Inc.	31,148,731.00	2024-10-11	107096409	5693589	1	orbimed	-20.22%	Decreased
46	SYRE	2025-09-30	Spyre Therapeutics, Inc.	46,620,133.00	2016-04-07	92657593	5528496	5	adar1-baker-perceptive-opaleye-tang	-1.44%	Decreased
47	DYN	2025-09-30	Dyne Therapeutics, Inc.	97,275,317.00	2020-09-17	92247482	7292291	5	adar1-deeptrack-logos-perceptive-orbimed	-51.11%	Decreased
48	AORT	2025-09-30	Artivion, Inc.	36,399,595.00	1993-02-12	85526800	2020000	1	perceptive	-27.69%	Decreased
49	KURA	2025-09-30	Kura Oncology, Inc.	59,769,977.00	2015-09-16	85355259	9644662	4	adar1-bvf-ecor1-tang	-20.22%	Decreased
50	IMNM	2025-09-30	Immunome, Inc.	69,554,437.00	2020-10-02	85066300	7264415	2	ecor1-opaleye	-4.53%	Decreased
51	BCYC	2025-09-30	Bicycle Therapeutics plc	NaN	2019-05-23	84252663	10885357	1	baker	-9.95%	Decreased
52	RARE	2025-09-30	Ultragenyx Pharmaceutical Inc.	89,184,961.00	2014-01-31	83673295	2781692	2	adar1-baker	-41.10%	Decreased
53	GLUE	2025-09-30	Monte Rosa Therapeutics, Inc.	33,917,745.00	2021-06-24	80605928	10877993	4	adar1-baker-bvf-casdin	-24.39%	Decreased
54	CLDX	2025-09-30	Celldex Therapeutics, Inc.	57,785,116.00	1986-05-15	71784387	2774812	3	adar1-baker-deeptrack	-16.49%	Decreased
55	ANIP	2025-09-30	ANI Pharmaceuticals, Inc.	16,794,626.00	2000-05-05	70303000	767500	2	deeptrack-tang	-24.57%	Decreased
56	NTRA	2025-09-30	Natera, Inc.	130,699,355.00	2015-07-01	69104421	429300	1	orbimed	-27.96%	Decreased
57	RAPT	2025-09-30	RAPT Therapeutics, Inc.	58,439,423.00	2019-10-31	65240988	2529701	4	adar1-deeptrack-perceptive-orbimed	-43.97%	Decreased
58	DSGN	2025-09-30	Design Therapeutics, Inc.	25,381,999.00	2021-03-29	57412906	7624556	4	baker-logos-racapital-tang	-1.67%	Decreased
59	ATXS	2025-09-30	Astria Therapeutics, Inc.	33,969,449.00	2015-06-25	52993697	7279354	4	adar1-logos-perceptive-tang	-3.39%	Decreased
60	OMDA	2025-09-30	Omada Health, Inc.	5,438,394.00	2025-06-06 09:30:00	52982856	2396330	1	perceptive	-15.21%	Decreased
61	ILMN	2025-09-30	Illumina, Inc.	157,885,200.00	2000-07-28	49859250	525000	1	casdin	-18.60%	Decreased
62	AVTX	2025-09-30	Avalo Therapeutics, Inc.	3,682,884.00	2015-10-14	46825979	3684184	6	adar1-bvf-deeptrack-perceptive-racapital-orbimed	-1.48%	Decreased
63	ENGN	2025-09-30	enGene Holdings Inc.	24,461,582.00	2022-02-01	45489057	6660184	3	cormorant-deeptrack-perceptive	-12.22%	Decreased
64	BIOA	2025-09-30	BioAge Labs, Inc.	23,819,840.00	2024-09-26	37700084	6411579	4	adar1-cormorant-orbimed-tang	-2.85%	Decreased
65	VRTX	2025-09-30	Vertex Pharmaceuticals Incorpor	256,181,277.00	1991-07-24	34072680	87000	2	adar1-tang	-60.51%	Decreased
66	EOLS	2025-09-30	Evolus, Inc. Common Stock	56,934,307.00	2018-02-08	33698156	5488299	1	tang	-26.55%	Decreased
67	ADMA	2025-09-30	ADMA Biologics Inc	232,872,303.00	2013-10-17	32302841	2203468	2	perceptive-tang	-6.37%	Decreased
68	CDXS	2025-09-30	Codexis, Inc.	63,397,051.00	2010-04-22	31219800	12795000	1	opaleye	-35.38%	Decreased
69	LRMR	2025-09-30	Larimar Therapeutics, Inc.	31,346,135.00	2014-06-19	30852659	10001907	3	adar1-racapital-opaleye	-3.76%	Decreased
70	ALMS	2025-09-30	Alumis Inc.	4,764,450.00	2024-06-28	30043180	7529619	6	adar1-baker-cormorant-orbimed-opaleye-tang	-10.85%	Decreased
71	ITGR	2025-09-30	Integer Holdings Corporation	32,987,365.00	2000-09-29	29965700	290000	1	orbimed	-33.09%	Decreased
72	SRPT	2025-09-30	Sarepta Therapeutics, Inc.	92,551,132.00	1997-06-04	29575731	1534807	3	adar1-opaleye-tang	-35.53%	Decreased
73	ZLAB	2025-09-30	Zai Lab Limited	983,033,752.00	2017-09-20	29442954	868780	1	adar1	-19.66%	Decreased
74	MNMD	2025-09-30	Mind Medicine (MindMed) Inc.	70,224,468.00	2016-11-15	29098003	2468024	3	deeptrack-orbimed-tang	-20.39%	Decreased
75	LEGN	2025-09-30	Legend Biotech Corporation	161,989,576.00	2020-06-05	27066300	830000	1	tang	-23.15%	Decreased
76	ABOS	2025-09-30	Acumen Pharmaceuticals, Inc.	32,793,241.00	2021-07-01	27057751	15823246	2	adar1-racapital	-0.16%	Decreased
77	KRRO	2025-09-30	Korro Bio, Inc.	4,913,494.00	2019-10-03	25747340	537635	3	adar1-cormorant-orbimed	-36.31%	Decreased
78	ELDN	2025-09-30	Eledon Pharmaceuticals, Inc.	46,043,696.00	2014-09-17	25536415	9859620	2	bvf-racapital	-0.17%	Decreased
79	MNKD	2025-09-30	MannKind Corporation	298,491,009.00	2004-07-28	23997869	4468877	1	avoro	-23.61%	Decreased
80	BCRX	2025-09-30	BioCryst Pharmaceuticals, Inc.	195,072,537.00	1994-03-04	22401885	2951500	3	avoro-orbimed-tang	-44.31%	Decreased
81	BIIB	2025-09-30	Biogen Inc.	146,001,681.00	1991-09-17	21432240	153000	3	adar1-logos-tang	-36.28%	Decreased
82	FBRX	2025-09-30	Forte Biosciences, Inc.	3,572,266.00	2017-04-13	18934575	1262305	2	bvf-orbimed	-31.90%	Decreased
83	CYBN	2025-09-30	Cybin Inc.	18,315,557.00	2019-09-13	16865278	2863375	3	adar1-deeptrack-tang	-14.78%	Decreased
84	VIR	2025-09-30	Vir Biotechnology, Inc.	92,043,716.00	2019-10-11	16691781	2923254	2	baker-orbimed	-7.88%	Decreased
85	RZLT	2025-09-30	Rezolute, Inc.	52,813,526.00	2013-01-14	16162520	1719417	2	adar1-opaleye	-9.16%	Decreased
86	CERS	2025-09-30	Cerus Corporation	158,448,986.00	1997-01-31	15913269	10008345	1	baker	-22.32%	Decreased
87	ARQT	2025-09-30	Arcutis Biotherapeutics, Inc.	85,242,758.00	2020-01-31	14608750	775000	1	cormorant	-22.50%	Decreased
88	PRTA	2025-09-30	Prothena Corporation plc	32,018,442.00	2012-12-18	14338396	1469098	1	adar1	-56.47%	Decreased
89	AVIR	2025-09-30	Atea Pharmaceuticals, Inc.	66,621,549.00	2020-10-30	13995980	4826200	1	tang	-1.29%	Decreased
90	CCCC	2025-09-30	C4 Therapeutics, Inc.	47,230,841.00	2020-10-02	13620024	6135146	2	orbimed-tang	-20.64%	Decreased
91	UNH	2025-09-30	UnitedHealth Group Incorporated	912,224,315.00	1984-10-17	9572010	27721	2	casdin-tang	-91.82%	Decreased
92	AGIO	2025-09-30	Agios Pharmaceuticals, Inc.	50,708,827.00	2013-07-24	9106401	226866	2	adar1-baker	-74.33%	Decreased
93	PLRX	2025-09-30	Pliant Therapeutics, Inc.	50,199,674.00	2020-06-03	8885100	6003446	1	tang	-40.15%	Decreased
94	AVR	2025-09-30	Anteris Technologies Global Cor	27,873,412.00	2024-12-13	8562353	1902745	2	adar1-perceptive	-14.93%	Decreased
95	SNY	2025-09-30	Sanofi	1,129,611,427.00	2002-07-01	8222806	174212	2	adar1-tang	-17.04%	Decreased
96	ALT	2025-09-30	Altimmune, Inc.	76,335,168.00	2017-05-26	8035027	2131307	1	tang	-22.50%	Decreased
97	SVRA	2025-09-30	Savara, Inc.	101,850,947.00	2017-04-28	7098188	1988288	1	adar1	-44.78%	Decreased
98	BLCO	2025-09-30	Bausch + Lomb Corporation	41,284,904.00	2022-05-06	6698118	444467	1	tang	-19.19%	Decreased
99	TEVA	2025-09-30	Teva Pharmaceutical Industries	1,128,838,460.00	1982-02-16	5409883	267816	1	adar1	-22.57%	Decreased
100	TECX	2025-09-30	Tectonic Therapeutic, Inc.	9,868,448.00	2018-06-21	5258864	335173	3	adar1-baker-tang	-87.54%	Decreased
101	ALGS	2025-09-30	Aligos Therapeutics, Inc.	4,373,872.00	2020-10-16	5166217	527165	2	baker-deeptrack	-21.12%	Decreased
102	RCKT	2025-09-30	Rocket Pharmaceuticals, Inc.	80,783,728.00	2015-02-18	4648108	1425800	2	adar1-tang	-15.02%	Decreased
103	AUTL	2025-09-30	Autolus Therapeutics plc	138,094,286.00	2018-06-22	4186839	2568613	1	deeptrack	-84.76%	Decreased
104	KZR	2025-09-30	Kezar Life Sciences, Inc.	4,911,032.00	2018-06-21	4046901	1037667	3	adar1-orbimed-tang	-2.12%	Decreased
105	ZURA	2025-09-30	Zura Bio Limited	46,618,074.00	2023-03-21	3945358	911168	2	adar1-deeptrack	-66.56%	Decreased
106	VYGR	2025-09-30	Voyager Therapeutics, Inc.	45,086,359.00	2015-11-11	3293765	705303	2	adar1-ecor1	-82.36%	Decreased
107	SNDX	2025-09-30	Syndax Pharmaceuticals, Inc.	76,941,078.00	2016-03-02	3077000	200000	1	tang	-76.74%	Decreased
108	TENX	2025-09-30	Tenax Therapeutics, Inc.	3,915,154.00	1994-04-04	2990555	392977	2	adar1-bvf	-20.63%	Decreased
109	ZNTL	2025-09-30	Zentalis Pharmaceuticals, Inc.	45,013,608.00	2020-04-03	2893991	1916550	3	adar1-opaleye-tang	-45.62%	Decreased
110	BHVN	2025-09-30	Biohaven Ltd.	84,648,084.00	2022-09-23	2616858	174341	3	adar1-cormorant-tang	-80.24%	Decreased
111	NMRA	2025-09-30	Neumora Therapeutics, Inc.	85,270,564.00	2023-09-14	2548000	1400000	1	tang	-42.50%	Decreased
112	TARA	2025-09-30	Protara Therapeutics, Inc.	30,107,039.00	2014-10-22	2488439	572055	2	adar1-baker	-77.60%	Decreased
113	MTD	2025-09-30	Mettler-Toledo International, I	20,572,592.00	1997-11-14	2417164	1969	1	tang	-89.90%	Decreased
114	FATE	2025-09-30	Fate Therapeutics, Inc.	99,964,480.00	2013-10-01	2353394	1867773	1	tang	-57.09%	Decreased
115	RGNX	2025-09-30	REGENXBIO Inc.	41,056,108.00	2015-09-17	1982197	205409	1	adar1	-1.16%	Decreased
116	KALA	2025-09-30	KALA BIO, Inc.	3,851,888.00	2017-07-20	1724444	1127088	2	adar1-baker	-43.93%	Decreased
117	LYRA	2025-09-30	Lyra Therapeutics, Inc.	46,626,967.00	2020-05-01	1497864	229382	1	perceptive	-10.10%	Decreased
118	IOVA	2025-09-30	Iovance Biotherapeutics, Inc.	251,861,761.00	2010-10-15	1179959	543760	1	tang	-69.79%	Decreased
119	BCAB	2025-09-30	BioAtla, Inc.	42,296,447.00	2020-12-16	945227	1374076	1	tang	-11.04%	Decreased
120	DNA	2025-09-30	Ginkgo Bioworks Holdings, Inc.	36,712,127.00	2021-04-19	532068	36493	1	casdin	-93.20%	Decreased
121	PHAT	2025-09-30	Phathom Pharmaceuticals, Inc.	56,653,838.00	2019-10-25	504933	42900	1	adar1	-32.36%	Decreased
122	SGRY	2025-09-30	Surgery Partners, Inc.	74,906,623.00	2015-09-30	432800	20000	1	adar1	-50.00%	Decreased
123	MGNX	2025-09-30	MacroGenics, Inc.	52,340,363.00	2013-10-10	367678	218856	1	tang	-87.99%	Decreased
124	BOLT	2025-09-30	Bolt Biotherapeutics, Inc.	27,481,128.00	2021-02-05	355796	66879	1	tang	-62.36%	Decreased
125	IBIO	2025-09-30	iBio, Inc.	8,599,460.00	2008-08-19	332776	402000	2	adar1-opaleye	-6.47%	Decreased
126	VYNE	2025-09-30	VYNE Therapeutics Inc.	10,466,058.00	2018-01-25	285203	851353	1	baker	-37.90%	Decreased
127	SAVA	2025-09-30	Cassava Sciences, Inc.	43,475,174.00	2000-07-14	256292	88073	2	adar1-tang	-63.28%	Decreased
128	SPRO	2025-09-30	Spero Therapeutics, Inc.	41,896,412.00	2017-11-02	217213	115539	1	adar1	-19.72%	Decreased
129	DAWN	2025-09-30	Day One Biopharmaceuticals, Inc	71,972,855.00	2021-05-27	197562	28023	1	adar1	-96.85%	Decreased
130	MGX	2025-09-30	Metagenomi, Inc.	23,310,838.00	2024-02-09	66379	28008	1	tang	-86.00%	Decreased
131	PHGE	2025-09-30	BiomX Inc.	17,770,088.00	2019-03-13	40769	77656	1	adar1	-74.08%	Decreased
132	OVID	2025-09-30	Ovid Therapeutics Inc.	50,468,940.00	2017-05-05	16700	12846	1	adar1	-99.68%	Decreased

------------------------------------------------------------
------------------------------------------------------------

Decreased Positions (when all funds shares were added together) Sorted by Decrease in Share %

	SYMBOL	DATE	Company	Float	First Traded	VALUE	SHARES	FUND_COUNT	FUND_LIST	PCT_CHANGE
0	OVID	2025-09-30	Ovid Therapeutics Inc.	50,468,940.00	2017-05-05	16700	12846	1	adar1	-99.68%
1	DAWN	2025-09-30	Day One Biopharmaceuticals, Inc	71,972,855.00	2021-05-27	197562	28023	1	adar1	-96.85%
2	DNA	2025-09-30	Ginkgo Bioworks Holdings, Inc.	36,712,127.00	2021-04-19	532068	36493	1	casdin	-93.20%
3	UNH	2025-09-30	UnitedHealth Group Incorporated	912,224,315.00	1984-10-17	9572010	27721	2	casdin-tang	-91.82%
4	MTD	2025-09-30	Mettler-Toledo International, I	20,572,592.00	1997-11-14	2417164	1969	1	tang	-89.90%
5	MGNX	2025-09-30	MacroGenics, Inc.	52,340,363.00	2013-10-10	367678	218856	1	tang	-87.99%
6	TECX	2025-09-30	Tectonic Therapeutic, Inc.	9,868,448.00	2018-06-21	5258864	335173	3	adar1-baker-tang	-87.54%
7	MGX	2025-09-30	Metagenomi, Inc.	23,310,838.00	2024-02-09	66379	28008	1	tang	-86.00%
8	AUTL	2025-09-30	Autolus Therapeutics plc	138,094,286.00	2018-06-22	4186839	2568613	1	deeptrack	-84.76%
9	VYGR	2025-09-30	Voyager Therapeutics, Inc.	45,086,359.00	2015-11-11	3293765	705303	2	adar1-ecor1	-82.36%
10	BHVN	2025-09-30	Biohaven Ltd.	84,648,084.00	2022-09-23	2616858	174341	3	adar1-cormorant-tang	-80.24%
11	TARA	2025-09-30	Protara Therapeutics, Inc.	30,107,039.00	2014-10-22	2488439	572055	2	adar1-baker	-77.60%
12	SNDX	2025-09-30	Syndax Pharmaceuticals, Inc.	76,941,078.00	2016-03-02	3077000	200000	1	tang	-76.74%
13	AGIO	2025-09-30	Agios Pharmaceuticals, Inc.	50,708,827.00	2013-07-24	9106401	226866	2	adar1-baker	-74.33%
14	PHGE	2025-09-30	BiomX Inc.	17,770,088.00	2019-03-13	40769	77656	1	adar1	-74.08%
15	IOVA	2025-09-30	Iovance Biotherapeutics, Inc.	251,861,761.00	2010-10-15	1179959	543760	1	tang	-69.79%
16	ZURA	2025-09-30	Zura Bio Limited	46,618,074.00	2023-03-21	3945358	911168	2	adar1-deeptrack	-66.56%
17	SAVA	2025-09-30	Cassava Sciences, Inc.	43,475,174.00	2000-07-14	256292	88073	2	adar1-tang	-63.28%
18	BOLT	2025-09-30	Bolt Biotherapeutics, Inc.	27,481,128.00	2021-02-05	355796	66879	1	tang	-62.36%
19	VRTX	2025-09-30	Vertex Pharmaceuticals Incorpor	256,181,277.00	1991-07-24	34072680	87000	2	adar1-tang	-60.51%

------------------------------------------------------------
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Decreased Positions (when all funds shares were added together) with the Highest Fund Number

	SYMBOL	DATE	Company	Float	First Traded	VALUE	SHARES	FUND_COUNT	FUND_LIST	PCT_CHANGE
0	EWTX	2025-09-30	Edgewise Therapeutics, Inc.	54,187,991.00	2021-03-26	681727622	42030063	8	adar1-baker-cormorant-perceptive-racapital-orbimed-opaleye-tang	-1.29%
1	SEPN	2025-09-30	Septerna, Inc.	19,629,806.00	2024-10-25	276580454	14703905	7	adar1-avoro-bvf-casdin-logos-perceptive-racapital	-0.67%
2	RVMD	2025-09-30	Revolution Medicines, Inc.	168,212,518.00	2020-02-13	848386711	18166739	7	adar1-baker-bvf-casdin-logos-opaleye-tang	-5.75%
3	ABVX	2025-09-30	Abivax SA	30,875,904.00	2023-10-20	502460358	5918261	7	adar1-baker-bvf-cormorant-logos-perceptive-orbimed	-31.83%
4	JANX	2025-09-30	Janux Therapeutics, Inc.	37,290,619.00	2021-06-11	393105449	16084511	7	adar1-cormorant-logos-perceptive-racapital-orbimed-tang	-4.96%
5	ALMS	2025-09-30	Alumis Inc.	4,764,450.00	2024-06-28	30043180	7529619	6	adar1-baker-cormorant-orbimed-opaleye-tang	-10.85%
6	PTGX	2025-09-30	Protagonist Therapeutics, Inc.	46,016,118.00	2016-08-11	445142315	6700923	6	adar1-bvf-deeptrack-logos-perceptive-opaleye	-21.94%
7	AVTX	2025-09-30	Avalo Therapeutics, Inc.	3,682,884.00	2015-10-14	46825979	3684184	6	adar1-bvf-deeptrack-perceptive-racapital-orbimed	-1.48%
8	XENE	2025-09-30	Xenon Pharmaceuticals Inc.	70,775,310.00	2014-11-05	312354835	7779697	6	adar1-avoro-baker-deeptrack-perceptive-orbimed	-8.78%
9	INSM	2025-09-30	Insmed Incorporated	166,410,802.00	2000-06-01	1159147003	8049073	5	baker-cormorant-perceptive-orbimed-tang	-25.93%
10	XNCR	2025-09-30	Xencor, Inc.	63,604,579.00	2013-12-03	125104179	10665318	5	adar1-baker-bvf-deeptrack-ecor1	-6.78%
11	CGON	2025-09-30	CG Oncology, Inc.	60,853,824.00	2024-01-25	124798195	3098267	5	adar1-cormorant-orbimed-opaleye-tang	-8.32%
12	SYRE	2025-09-30	Spyre Therapeutics, Inc.	46,620,133.00	2016-04-07	92657593	5528496	5	adar1-baker-perceptive-opaleye-tang	-1.44%
13	DYN	2025-09-30	Dyne Therapeutics, Inc.	97,275,317.00	2020-09-17	92247482	7292291	5	adar1-deeptrack-logos-perceptive-orbimed	-51.11%
14	IRON	2025-09-30	Disc Medicine, Inc.	26,301,510.00	2020-08-12	262532470	3972949	5	baker-logos-racapital-orbimed-opaleye	-5.76%
15	AXSM	2025-09-30	Axsome Therapeutics, Inc.	36,674,021.00	2015-11-19	263237653	2167457	5	bvf-cormorant-deeptrack-perceptive-orbimed	-32.65%
16	GHRS	2025-09-30	GH Research PLC	17,280,108.00	2021-06-25	281636756	19694878	5	bvf-cormorant-deeptrack-racapital-tang	-3.99%
17	TSHA	2025-09-30	Taysha Gene Therapies, Inc.	127,701,667.00	2020-09-24	173297195	52996084	5	adar1-avoro-baker-racapital-tang	-0.33%
18	MRUS	2025-09-30	Merus N.V.	55,639,246.00	2016-05-19	574624095	6103283	5	adar1-avoro-baker-perceptive-tang	-5.40%
19	APLS	2025-09-30	Apellis Pharmaceuticals, Inc.	84,226,131.00	2017-11-09	588677087	26013128	5	adar1-avoro-deeptrack-ecor1-orbimed	-20.25%

------------------------------------------------------------
------------------------------------------------------------

Unchanged Positions (when all funds shares were added together) Sorted by Value

	SYMBOL	DATE	Company	Float	First Traded	VALUE	SHARES	FUND_COUNT	FUND_LIST
0	HROW	2025-09-30	Harrow, Inc.	26,130,229.00	2007-09-28	188142900	3905000	1	opaleye
1	SYK	2025-09-30	Stryker Corporation	343,306,737.00	1980-03-17	132785464	359200	1	orbimed
2	CAI	2025-09-30	None	NaN	2025-06-18 09:30:00	125023885	4133021	2	perceptive-orbimed
3	XOMA	2025-09-30	XOMA Royalty Corporation	8,907,733.00	1986-06-06	109661331	2845390	2	bvf-opaleye
4	ETON	2025-09-30	Eton Pharmaceuticals, Inc.	20,737,195.00	2018-11-13	106271521	4890544	2	ecor1-opaleye
5	MGTX	2025-09-30	MeiraGTx Holdings plc	31,284,119.00	2018-06-08	103792540	12626103	1	perceptive
6	GRAL	2025-09-30	GRAIL, Inc.	22,501,359.00	2024-06-12	96389291	1630125	1	baker
7	CRVS	2025-09-30	Corvus Pharmaceuticals, Inc.	52,153,182.00	2016-03-23	63408539	8603601	2	perceptive-orbimed
8	ACIU	2025-09-30	AC Immune SA	39,596,052.00	2016-09-23	57286840	19822436	1	bvf
9	AVBP	2025-09-30	ArriVent BioPharma, Inc.	15,838,962.00	2024-01-26	55854202	3027328	1	orbimed
10	CGEM	2025-09-30	Cullinan Therapeutics, Inc.	38,980,660.00	2021-01-08	52158358	8795676	3	bvf-orbimed-tang
11	SIBN	2025-09-30	SI-BONE, Inc.	37,756,528.00	2018-10-17	37962571	2578979	1	orbimed
12	NKTX	2025-09-30	Nkarta, Inc.	48,884,788.00	2020-07-10	36971659	17860705	2	racapital-tang
13	SNWV	2025-09-30	SANUWAVE Health, Inc.	5,600,874.00	2025-03-03	36730400	980000	1	opaleye
14	AVDL	2025-09-30	Avadel Pharmaceuticals plc	84,810,689.00	1996-06-07	32028825	2097500	1	tang
15	PRLD	2025-09-30	Prelude Therapeutics Incorporat	16,835,400.00	2020-09-25	30287636	21033080	2	baker-orbimed
16	TRDA	2025-09-30	Entrada Therapeutics, Inc.	19,019,077.00	2021-10-29	28221750	4865819	1	baker
17	NPCE	2025-09-30	Neuropace, Inc.	21,126,966.00	2021-04-22	26952237	2614184	1	orbimed
18	FHTX	2025-09-30	Foghorn Therapeutics Inc.	25,845,788.00	2020-10-23	25926780	5302000	1	bvf
19	RPTX	2025-09-30	Repare Therapeutics Inc.	22,476,262.00	2020-06-19	24034715	13656088	2	bvf-orbimed
20	TGTX	2025-09-30	TG Therapeutics, Inc.	134,539,735.00	2010-05-03	22939375	635000	2	opaleye-tang
21	TMO	2025-09-30	Thermo Fisher Scientific Inc	376,446,298.00	1980-03-17	22553430	46500	1	orbimed
22	ACET	2025-09-30	Adicet Bio, Inc.	61,366,056.00	2018-01-26	22046961	27211752	3	racapital-orbimed-tang
23	GSK	2025-09-30	GSK plc	3,947,946,444.00	1980-03-28	17264000	400000	1	tang
24	SERA	2025-09-30	Sera Prognostics, Inc.	24,854,185.00	2021-07-15	16824400	5498170	1	baker
25	TCRX	2025-09-30	TScan Therapeutics, Inc.	37,137,033.00	2021-07-16	15671776	8610866	3	baker-bvf-tang
26	RCUS	2025-09-30	Arcus Biosciences, Inc.	65,841,832.00	2018-03-15	15454550	1136364	1	racapital
27	ACRV	2025-09-30	Acrivon Therapeutics, Inc.	11,274,619.00	2022-11-15	15137603	8363317	2	baker-racapital
28	DBVT	2025-09-30	DBV Technologies S.A.	28,773,868.00	2014-10-22	14614250	1461425	1	baker
29	HOWL	2025-09-30	Werewolf Therapeutics, Inc.	26,381,231.00	2021-04-30	13162175	6681307	1	racapital
30	OM	2025-09-30	Outset Medical, Inc.	2,773,914.00	2020-09-15	11766661	833333	1	perceptive
31	VNDA	2025-09-30	Vanda Pharmaceuticals Inc.	51,637,107.00	2006-04-12	11743002	2353307	1	tang
32	AZN	2025-09-30	Astrazeneca PLC	1,544,514,614.00	1993-05-12	11508000	150000	1	tang
33	TDOC	2025-09-30	Teladoc Health, Inc.	159,717,484.00	2015-06-30	10822000	1400000	1	tang
34	NAUT	2025-09-30	Nautilus Biotechnology, Inc.	46,630,782.00	2020-08-07	10642108	12594211	1	perceptive
35	IDXX	2025-09-30	IDEXX Laboratories, Inc.	80,436,876.00	1991-06-21	10222240	16000	1	tang
36	VCYT	2025-09-30	Veracyte, Inc.	77,565,181.00	2013-10-30	9485654	276308	1	casdin
37	CHRS	2025-09-30	Coherus BioSciences, Inc.	114,413,369.00	2014-11-06	8376674	5107728	2	adar1-tang
38	ATRA	2025-09-30	Atara Biotherapeutics, Inc.	4,197,850.00	2014-10-16	8213712	573183	1	ecor1
39	MRNA	2025-09-30	Moderna, Inc.	359,997,079.00	2018-12-07	7885899	305300	1	tang
40	BDTX	2025-09-30	Black Diamond Therapeutics, Inc	38,983,042.00	2020-01-31	7846092	2070209	1	tang
41	SRZN	2025-09-30	Surrozen, Inc.	2,128,396.00	2021-01-11	7764836	602626	1	racapital
42	CNTX	2025-09-30	Context Therapeutics Inc.	40,555,266.00	2021-10-20	7528011	7770449	2	adar1-deeptrack
43	BMEA	2025-09-30	Biomea Fusion, Inc.	29,397,656.00	2021-04-16	7213161	3570872	1	cormorant
44	SANA	2025-09-30	Sana Biotechnology, Inc.	134,123,841.00	2021-02-04	7209869	2030949	1	baker
45	IMUX	2025-09-30	Immunic, Inc.	64,834,702.00	2014-04-17	6746860	7652972	1	bvf
46	SGMT	2025-09-30	Sagimet Biosciences Inc. – Seri	19,428,281.00	2023-07-17	6537553	952996	1	baker
47	IBRX	2025-09-30	ImmunityBio, Inc.	204,851,716.00	2015-07-28	5739999	2333333	1	tang
48	SKYE	2025-09-30	Skye Bioscience, Inc.	15,691,401.00	2015-01-06	5701007	1450638	1	baker
49	NSPR	2025-09-30	InspireMD Inc.	16,807,131.00	2011-04-12	5141506	2133405	1	orbimed
50	MOLN	2025-09-30	Molecular Partners AG	14,882,000.00	2021-06-16	5023221	1353968	1	bvf
51	QTTB	2025-09-30	Q32 Bio Inc.	5,426,353.00	2018-03-28	4460914	2252987	1	orbimed
52	IVA	2025-09-30	Inventiva S.A. – American Depos	24,956,237.00	2020-07-10	3972172	686040	1	bvf
53	TBPH	2025-09-30	Theravance Biopharma, Inc.	21,119,514.00	2014-05-16	3858897	264308	1	tang
54	DTIL	2025-09-30	Precision BioSciences, Inc.	8,756,605.00	2019-03-28	3608142	653649	1	tang
55	ABSI	2025-09-30	Absci Corporation	100,727,471.00	2021-07-22	2958710	973260	1	casdin
56	SEER	2025-09-30	Seer, Inc.	41,961,608.00	2020-12-04	2917398	1344423	1	tang
57	LNTH	2025-09-30	Lantheus Holdings, Inc.	61,829,554.00	2015-06-25	2564500	50000	1	tang
58	OPRX	2025-09-30	OptimizeRx Corporation	14,276,611.00	2007-11-28	2050000	100000	1	tang
59	TRIB	2025-09-30	Trinity Biotech plc	181,493,781.00	1992-10-21	1861600	1790000	1	perceptive
60	JNJ	2025-09-30	Johnson & Johnson	2,403,933,039.00	1962-01-02	1756213	9472	1	tang
61	ENTA	2025-09-30	Enanta Pharmaceuticals, Inc.	14,292,378.00	2013-03-21	1516060	126655	1	tang
62	CDNA	2025-09-30	CareDx, Inc.	54,071,844.00	2014-07-17	1454000	100000	1	tang
63	VTRS	2025-09-30	Viatris Inc.	1,185,535,855.00	1980-03-17	1270749	128359	1	tang
64	MURA	2025-09-30	Mural Oncology plc	12,903,301.00	2023-11-24	1243356	600655	2	adar1-orbimed
65	TRAW	2025-09-30	Traws Pharma, Inc.	4,277,814.00	2013-07-25	1120232	605531	1	orbimed
66	PBYI	2025-09-30	Puma Biotechnology Inc	42,095,259.00	2012-04-24	1062000	200000	1	tang
67	IPSC	2025-09-30	Century Therapeutics, Inc.	39,812,176.00	2021-06-18	1059839	2128190	2	casdin-tang
68	RXRX	2025-09-30	Recursion Pharmaceuticals, Inc.	382,695,117.00	2021-04-16	977576	200323	2	adar1-casdin
69	FTRE	2025-09-30	Fortrea Holdings Inc.	78,282,776.00	2023-06-20	842000	100000	1	tang
70	LYEL	2025-09-30	Lyell Immunopharma, Inc.	201,520,273.00	2021-06-17	840046	51727	1	orbimed
71	XERS	2025-09-30	Xeris Biopharma Holdings, Inc.	146,657,227.00	2018-06-21	654619	80420	1	orbimed
72	TNYA	2025-09-30	Tenaya Therapeutics, Inc.	55,205,093.00	2021-07-30	586390	361969	1	casdin
73	APYX	2025-09-30	Apyx Medical Corporation	29,121,701.00	2019-01-02	321000	150000	1	perceptive
74	TXMD	2025-09-30	TherapeuticsMD, Inc.	9,513,315.00	2007-05-09	224901	209210	1	adar1
75	ENSC	2025-09-30	Ensysce Biosciences, Inc.	896,490.00	2018-03-14	205398	86666	1	perceptive
76	CLOV	2025-09-30	Clover Health Investments, Corp	400,755,222.00	2020-06-12	147798	48300	1	adar1
77	OGN	2025-09-30	Organon & Co.	256,822,907.00	2021-05-14	106800	10000	1	adar1
78	SLN	2025-09-30	Silence Therapeutics Plc – Amer	66,438,057.00	2020-09-08	96757	18643	1	adar1
79	NERV	2025-09-30	Minerva Neurosciences, Inc	5,437,023.00	2014-07-01	26115	12406	1	adar1
80	PRQR	2025-09-30	ProQR Therapeutics N.V.	64,438,464.00	2014-09-18	21300	10000	1	adar1
81	OPT	2025-09-30	Opthea Limited	785,981,303.00	2020-10-16	0	2087320	1	baker

------------------------------------------------------------
------------------------------------------------------------

13F positions: 
New: ASMB,ATAI,ATHA,BDSX,BLTE,BTSG,CARL,CGTX,CI,COGT,DHR,EPRX,EQ,ESPR,EVH,GBIO,GKOS,GUTS,HTFL,IMA,IMRX,INBS,INSP,IRTC,KPTI,MASI,MIST,MREO,NVCR,PASG,PGEN,PGNY,PLX,RIGL,SLGL,SUPN,TEM,TMCI,VOR,XFOR
Increased: ABUS,ACAD,ACHV,ACLX,ACRS,ADCT,AKRO,ALDX,ALKS,AMLX,ANAB,ANNX,ANRO,APGE,AQST,ARVN,ARWR,ASND,ATYR,AUPH,BBIO,BEAM,BHC,BMRN,BNTX,CABA,CBIO,CDTX,CELC,CMPS,CMPX,CNTA,CRBP,CRMD,CRNX,CRSP,CTMX,CTNM,DCTH,DERM,DNLI,DRUG,ERAS,ESTA,EXAS,EYPT,FDMT,FENC,FULC,GLPG,GMAB,GOSS,GPCR,HRMY,HRTX,IDYA,IFRX,IKT,IMCR,IMTX,IMVT,INBX,INCY,ISRG,IVVD,KALV,KNSA,KOD,KPRX,KRYS,LAB,LENZ,LQDA,LUNG,LXEO,MBX,MDGL,MLYS,MNPR,MRK,NAMS,NGNE,NKTR,NRIX,NTLA,NUVB,NUVL,NVNO,OABI,OBIO,OCUL,OLMA,ORIC,PACB,PCVX,PEN,PEPG,PFE,PHVS,PMVP,PRAX,PRME,PTCT,PYXS,QNCX,QURE,RAPP,REGN,REPL,RGEN,RNA,ROIV,RYTM,SABS,SLNO,SMMT,SPRY,SRRK,STOK,STRO,STTK,TARS,TNGX,TRVI,TVTX,UNCY,URGN,VKTX,VRDN,VSTM,VTGN,VTVT,VTYX,WVE,ZYME
Closed: ACHC,ACTU,ALEC,ALXO,ANIK,APLT,ARDX,AVXL,CADL,CASI,CPRX,CRL,ELAN,GALT,GMED,HNGE,INO,MCRB,NVAX,PCRX,PODD,PYPD,RCEL,RLMD,RNXT,RXST,THC,TPST,TXG
Decreased: ABCL,ABOS,ABVX,ADMA,AGIO,ALGS,ALMS,ALNY,ALT,ANIP,AORT,APLS,ARGX,ARQT,ATXS,AUTL,AVIR,AVR,AVTX,AXSM,BCAB,BCAX,BCRX,BCYC,BHVN,BIIB,BIOA,BLCO,BLFS,BOLT,BSX,CCCC,CDXS,CERS,CGON,CLDX,CYBN,CYTK,DAWN,DNA,DNTH,DSGN,DVAX,DYN,ELDN,ELVN,ENGN,EOLS,EW,EWTX,FATE,FBRX,FOLD,GERN,GH,GHRS,GLUE,IBIO,ILMN,IMNM,INSM,IONS,IOVA,IRON,ITGR,JANX,JAZZ,KALA,KROS,KRRO,KURA,KYMR,KZR,LEGN,LLY,LRMR,LYRA,MGNX,MGX,MIRM,MLTX,MNKD,MNMD,MRUS,MTD,NBIX,NMRA,NTRA,OMDA,OVID,PHAT,PHGE,PLRX,PRTA,PTGX,RAPT,RARE,RCKT,RGNX,RLAY,RVMD,RZLT,SAVA,SEPN,SGRY,SLDB,SNDX,SNY,SPRO,SRPT,SVRA,SYRE,TARA,TECX,TENX,TERN,TEVA,TSHA,TYRA,UNH,UPB,UTHR,VERA,VIR,VRTX,VYGR,VYNE,WGS,XENE,XNCR,ZLAB,ZNTL,ZURA
Unchanged: ABSI,ACET,ACIU,ACRV,APYX,ATRA,AVBP,AVDL,AZN,BDTX,BMEA,CAI,CDNA,CGEM,CHRS,CLOV,CNTX,CRVS,DBVT,DTIL,ENSC,ENTA,ETON,FHTX,FTRE,GRAL,GSK,HOWL,HROW,IBRX,IDXX,IMUX,IPSC,IVA,JNJ,LNTH,LYEL,MGTX,MOLN,MRNA,MURA,NAUT,NERV,NKTX,NPCE,NSPR,OGN,OM,OPRX,OPT,PBYI,PRLD,PRQR,QTTB,RCUS,RPTX,RXRX,SANA,SEER,SERA,SGMT,SIBN,SKYE,SLN,SNWV,SRZN,SYK,TBPH,TCRX,TDOC,TGTX,TMO,TNYA,TRAW,TRDA,TRIB,TXMD,VCYT,VNDA,VTRS,XERS,XOMA

End of Report - 2025-11-15 05:22:19

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